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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Diabetes, obesity, and insulin resistance in COVID-19: molecular interrelationship and therapeutic implications

Fig. 2

Clinical manifestations and complications of this insulin resistance syndrome and the parallel with obesity/diabetes. T2D and obesity, without infections, have an increase in the basal inflammatory response and a potential decrease in an interferon response. Thus, the synergy between COVID-19 and T2D/obesity may amplify the inflammatory response and downregulate even more the interferon response, contributing to more severe disease in these patients

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