Fig. 2From: Diabetes, obesity, and insulin resistance in COVID-19: molecular interrelationship and therapeutic implicationsClinical manifestations and complications of this insulin resistance syndrome and the parallel with obesity/diabetes. T2D and obesity, without infections, have an increase in the basal inflammatory response and a potential decrease in an interferon response. Thus, the synergy between COVID-19 and T2D/obesity may amplify the inflammatory response and downregulate even more the interferon response, contributing to more severe disease in these patientsBack to article page