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Table 1 Characteristics of the studies included in the systematic review about Brazilian women with PCOS

From: Metabolic profile of women with PCOS in Brazil: a systematic review and meta-analysis

Name, Year Region PCOS criteria Type of studies N (PCOS/controls) Age (PCOS/controls
BMI-unmatched studies
Avila et al. 2014 [30] Southeast Rotterdam Cross-sectional 100/– 25.7 ± 4.9/–
Azevedo et al. 2011 [23] Northeast Rotterdam Cross-sectional 113/242 26.2 ± 4.3/ 26.8 ± 5.0
Carvalho et al. 2017 [31] Southeast Rotterdam Case–control 86/86 31.1 ± 4.92/29.0 ± 7.04
Cerqueira et al. 2010 [24] Northeast Rotterdam Cross-sectional 56/54 26.2 ± 6.0/27.7 ± 6.1
Costa et al. 2012 [29] Northeast Rotterdam Cross-sectional 113/– 27.2 ± 4.5/–
de Medeiros et al. 2014 [48] Midwest Rotterdam Cross-sectional 288/– 26.9 ± 5.5/–
Gabrielli et al. 2012 [26] Northeast Rotterdam Cross-sectional 73/725 28.4 ± 6.5/31.0 ± 7.3*
Graff et al. 2017 [44] South Rotterdam Case–control 84/54 23.5 ± 6.3/26.2 ± 6.5
Kogure et al. 2012 [32] Southeast Rotterdam Case–control 20/19 27.8 ± 5.0/27.9 ± 5.2
Maciel et al. 2014 [34] Southeast Rotterdam Cross-sectional 97/– 24.9 ± 5.1/–
Melo et al. 2011a [35] Southeast Rotterdam Cross-sectional 132/146 26.6 ± 5.1/28.9 ± 0.5
Oliveira et al. 2013b [36] Southeast Rotterdam Case–control 42/18 27.4 ± 5.5/31.4 ± 6.1
Pedroso et al. 2012 [37] Southeast Rotterdam Cross-sectional 105/– 29 ± 4.4/–
Pontes et al. 2012 [38] Southeast Rotterdam Cross-sectional 189/– 24.9 ± 5.2/–
Radavelli-Bagatini et al. 2013 [45] South Rotterdam Case–control 80/1500 21.3 ± 0.6/22.7 ± 0.4
Ramos et al. 2015 [46] South Rotterdam Case–control 199/99 22 ± 6/25 ± 7
Santana et al. 2004c [40] Southeast NIH Cohort 21/– 27.2/–
Soares et al. 2016 [27] Northeast Rotterdam Cross-sectional 22/– 26 ± 6.0/–
Tavares et al. 2019 [28] Northeast Rotterdam Cross-sectional 111/– 18–39
Wanderley et al., 2018 [49] Midwest Rotterdam Cross-sectional 83/– 28.79 ± 5.85/–
Wiltgen et al. 2010d [43] South Rotterdam Case–control 195/25 22.3 ± 6.7/29.7 ± 4.29*
Xavier et al. 2018 [42] Southeast Rotterdam Case–control 97/99 30.5 ± 5.1/29.8 ± 7.1
BMI-matched studies
Costa et al., 2008 [25] Northeast Rotterdam Cross-sectional 57/37 25.5 ± 5.3/26.6 ± 5.4
Lauria et al. 2013 [33] Southeast Rotterdam Case–control 40/36 29 (25–34)/30(15–43)
Rocha et al. 2011 [39] Southeast Rotterdam Case–control 142/31 25.1 ± 5.4/27.5 ± 4
Simões et al. 2017 [41] Southeast Rotterdam Case–control 10/10 29.6 ± 1.2/28.6 ± 2.0
Wiltgen et al. 2009 [47] South Rotterdam Case–control 51/44 20.6 ± 5.1/28.9 ± 5.6*
  1. aData are from A phenotype PCOS vs controls
  2. bWomen included in the control group had similar complaints as the ones from the PCOS group, but did not fulfill the diagnostic criteria
  3. cData are from baseline
  4. dData are from A plus B phenotypes PCOS vs controls
  5. *p < 0.05 between groups