Table 3 Changes in baseline to endpoint measures for SIRT1, Fetuin-A and HOMA-IR in two groups
Variables | Mean ± SD Placebo(n = 21) | Mean ± SD Intervention(n = 21) | P1 |
|---|---|---|---|
FBS (mg/dl) | |||
Baseline | 163.28 ± 7.90 | 160.80 ± 8.94 | 0.811 |
End | 162.52 ± 8.54 | 123.47 ± 9.73 | 0.022 |
P2 | 0.91 | 0.011 | |
Mean changes | − 0.76 ± 0.64 | − 37.33 ± 0.79 | 0.032 |
Insulin (µU/ml) | |||
Baseline | 16.08 ± 0.77 | 15.83 ± .88 | 0.53 |
End | 16.00 ± .84 | 12.16 ± .96 | .031 |
P2 | 0.77 | 0.03 | |
Mean changes | − 0.08 ± 0.07 | − 3.67 ± 0.08 | 0.039 |
HOMA-IR | |||
Baseline | 6.49 ± .63 | 6.30 ± .72 | 0.45 |
End | 6.43 ± .68 | 3.72 ± .58 | 0.038 |
P2 | 0.59 | 0.02 | |
Mean changes | − 0.06 ± 0.05 | − 2.58 ± 0.14 | 0.042 |
Fetuin-A (µg/ml) | |||
Baseline | 123.58 ± 24.11 | 119.8 ± 25.07 | 0.21 |
End | 121.63 ± 24.01 | 101.31 ± 19.07 | 0.031 |
P2 | 0.159 | 0.022 | |
Mean changes | − 1.95 ± 0.1 | − 18.49 ± 6 | 0.033 |
SIRT1 (ng/mL) | |||
Baseline | 6.04 ± 0.04 | 5.96 ± 0.05 | 0.46 |
End | 6.02 ± 0.03 | 6.94 ± 0.09 | 0.033 |
P2 | 0.66 | 0.01 | |
Mean changes | − 0.02 ± 0.01 | + 0.98 ± 0.04 | 0.046 |