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Table 4 Sensitivity, specificity, PPV, and NPV for CBG and HbA1c vs. VPG based on cut points defined by ROC curve analysis

From: Performance of diabetes screening tests: an evaluation study of Iranian diabetes screening program

Screening test Reference n Sensitivity Specificity PPV NPV
CBG VPG 1057 57/71 (80.28%) 879/986 (89.14%) 57/164 (34.75%) 879/893 (98.43%)
HbA1c VPG 1057 55/71 (77.46%) 929/986 (94.21%) 55/112 (49.10%) 929/945 (98.30%)
Pa    0.001 0.001   
  1. CBG ≥ 116.50(mg/dl); VPG ≥ 126 (mg/dl) and clinical diagnosis
  2. PPV positive predictive value, NPV negative predictive value
  3. HbA1c ≥ 7.15; acompared with indexes based on WHO’s recommendation cut points (CBG ≥ 126 mg/dl and HbA1c ≥ 6.5%)