Fig. 8

Exosomes derived from LPS-induced HK2 cells mediated the release of circ-FANCA. a Electron micrograph of exosomes isolated from the culture medium of LPS-treated HK2 cells or untreated HK2 cells. The scale bar represents 100 nm. b Western blot analysis for exosome markers (CD9 and CD63) in HK2 cells. c QRT-PCR assay for the expression level of exo-circ-FANCA in HK2 cells treated with LPS. d QRT-PCR assay for the expression of circ-FANCA in HK2 cells co-incubated with exosomes derived from LPS-induced HK2 cells or PBS. e QRT-PCR assay for the expression of exo-circ-FANCA in LPS-treated HK2 cells co-incubated with GW4869 or not. **P < 0.01, ***P < 0.001, ****P < 0.0001