Fig. 5

OXSR1 was a direct target of miR-93-5p. a The potential binding sites between miR-93-5p and OXSR1 were exhibited. b, c Dual-luciferase reporter assay and RIP assay were performed to verify whether OXSR1 could interact with miR-93-5p. d The mRNA level of OXSR1 in the serums of septic AKI patients (n = 19) and healthy controls (n = 19) was measured by qRT-PCR assay. e The correlation between OXSR1 mRNA and miR-93-5p in the serums of septic AKI patients was analyzed by Spearman’s correlation coefficient analysis. f The protein expression of OXSR1 in HK2 cells treated with different concentrations of LPS was quantified by western blot. g The protein level of OXSR1 in LPS-induced HK2 cells with miR-93-5p knockdown or overexpression was tested by western blot. **P < 0.01, ***P < 0.001, ****P < 0.0001