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Table 2 Correlations between BMI changes and delta of gene expression in adipose tissue at 3 and 6 months after RYGB

From: Bariatric surgery can acutely modulate ER-stress and inflammation on subcutaneous adipose tissue in non-diabetic patients with obesity

 

Correlation statistics

 

Correlation statistics

Pearson’s r

p value

Pearson’s r

p value

3 months

  

6 months

  

 IL6

0.362

0.548

 IL6

-0.305

0.5046

 TNFα

0.344

0.570

 TNFα

-0.555

0.1954

 MCP1

0.497

0.394

 MCP1

0.183

0.6942

 ADIPOQ

-0.066

0.915

ADIPOQ

0.950

0.0010

PGC1α

0.961

0.009

 PGC1α

0.386

0.3915

 PPARγ

0.384

0.523

 PPARγ

0.591

0.1623

 EIF2AK3

0.511

0.379

 EIF2AK3

0.165

0.7233

 ATF4

0.648

0.237

ATF4

-0.373

0.4097

 ATF6

0.410

0.492

ATF6

0.677

0.0945

 CHOP

0.254

0.680

CHOP

-0.286

0.5332

GRP78

0.261

0.671

GRP78

0.46

0.2987

GADD34

-0.554

0.332

GADD34

-0.05

0.9141

XBP1

-0.609

0.275

XBP1

0.232

0.6164

CALR

0.004

0.994

CALR

0.416

0.3523

CANX

0.490

0.401

CANX

0.743

0.0554

CCT4

0.637

0.247

CCT4

0.272

0.5539

SIRT1

0.958

0.010

SIRT1

0.844

0.0169

SIRT3

0.407

0.496

SIRT3

0.489

0.2646

AMPK

0.947

0.015

AMPK

0.692

0.0846

GCN2

-0.511

0.379

GCN2

0.278

0.5459

NRF2

0.127

0.839

NRF2

-0.014

0.9757

SOD1

-0.342

0.573

SOD1

-0.527

0.2232

SOD2

-0.710

0.178

SOD2

-0.112

0.8102

SOD3

-0.466

0.428

SOD3

0.105

0.8227

  1. IL6: Interleukin 6; TNF-ɑ: Tumor necrosis factor-α; MCP-1: Monocyte chemoattractant protein-1; PGC1ɑ: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PPARϒ: Peroxisome proliferator activated receptor gamma; EIF2AK3: Eukaryotic translation initiation factor 2 alpha kinase 3; ATF4: Activating Transcription Factor 4; ATF6: Activating Transcription Factor 6; CHOP: C/EBP homologous protein; GRP78: Heat shock protein family A (Hsp70) member 5; GADD34: growth arrest and DNA damage-inducible protein; XBP1: X-box binding protein 1; CARL: Calreticulin; CANX: Calnexin; CCT4: Chaperonin Containing TCP1 Subunit 4; SIRT1: Sirtuin 1; SIRT3: Sirtuin 3; AMPK: AMP-activated protein kinase; GCN2: General control nonderepressible 2; NRF2: Nuclear factor erythroid 2-related factor 2; SOD1: Superoxide dismutase 1; SOD2: Superoxide dismutase 2, SOD3: Superoxide dismutase 3
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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