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Table 5 Odds of the dementia in Alzheimer’s type or VD according to vascular risk factors

From: Associations between metabolic syndrome and type of dementia: analysis based on the National Health Insurance Service database of Gangwon province in South Korea

 

Alzheimer’s disease

Vascular dementia

Model 1

Model 2

Model 3

Model 1

Model 2

Model 3

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

p value

BMI

1.059 (1.042, 1.075)

< 0.0001

0.958 (0.941, 0.975)

< 0.0001

0.951 (0.927, 0.975)

< 0.0001

1.008 (0.984, 1.032)

0.528

0.998 (0.973, 1.023)

0.857

0.988 (0.952, 1.024)

0.504

Systolic BP

1.014 (1.011, 1.017)

< 0.0001

1.000 (0.995, 1.004)

0.882

0.999 (0.992, 1.005)

0.651

1.000 (0.996, 1.005)

0.855

0.994 (0.988, 1.000)

0.063

0.999 (0.990, 1.008)

0.788

Diastolic BP

1.014 (1.009, 1.018)

< 0.0001

0.996 (0.990, 1.002)

0.214

1.001 (0.991, 1.010)

0.916

1.007 (0.999, 1.014)

0.071

1.002 (1.002, 1.022)

0.019

1.004 (0.990, 1.019)

0.575

Fasting glucose

1.009 (1.008, 1.011)

< 0.0001

1.004 (1.002, 1.005)

< 0.0001

1.003 (1.001, 1.005)

0.003

1.005 (1.003, 1.007)

< 0.0001

1.002 (1.002, 1.007)

 < 0.0001

1.004 (1.001, 1.008)

0.012

Total cholesterol

1.001 (1.000, 1.002)

0.003

1.001 (1.000, 1.002)

0.211

1.000 (0.998, 1.002)

0.793

1.000 (0.999, 1.002)

0.662

0.999 (0.999, 1.002)

0.793

1.000 (0.997, 1.003)

0.998

Smoking

1.007 (0.994, 1.021)

0.282

  

1.020 (1.003, 1.039)

0.024

0.928 (0.892, 0.966)

< 0.0001

  

0.988 (0.962, 1.014)

0.352

Alcohol

0.995 (0.969, 1.021)

0.694

  

0.979 (0.940, 1.019)

0.302

0.972 (0.936, 1.011)

0.155

  

1.014 (0.972, 1.056)

0.525

Physical inactivity

0.935 (0.945, 1.163)

0.415

  

0.997 (0.838, 1.188)

0.977

0.974 (0.836, 1.136)

0.741

  

0.898 (0.700, 1.153)

0.399

Previous stroke

2.248 (1.757, 2.874)

< 0.0001

  

1.827 (1.263, 2.644)

0.001

2.461 (1.753, 3.445)

 < 0.0001

  

2.775 (1.747, 4.406)

< 0.0001

Previous cardiac disease

1.213 (1.004, 1.467)

0.046

  

1.088 (0.836, 1.416)

0.532

0.825 (0.598, 1.139)

0.242

  

0.702 (0.434, 1.136)

0.150

  1. Model 1: separate models associated each exposure variable with AD or VD with adjustment for age and sex
  2. Model 2: single model including age, sex, metabolic syndrome, BMI, systolic BP, diastolic BP, fasting glucose, total cholesterol
  3. Model 3: single model including age, sex, metabolic syndrome, BMI, systolic BP, diastolic BP, fasting glucose, total cholesterol, smoking, alcohol, physical inactivity, previous stroke and previous cardiac disease
  4. OR odds ratio, CI confidence interval, BMI body mass index, BP blood pressure