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Table 2 Metabolic syndrome and odds of dementia in Alzheimer’s type

From: Associations between metabolic syndrome and type of dementia: analysis based on the National Health Insurance Service database of Gangwon province in South Korea

  Model 1 Model 2 Model 3
OR (95% CI) p value OR (95% CI) p value OR (95% CI) p value
MetS 10.58 (9.02, 12.41) < 0.0001 12.03 (9.58, 15.10) < 0.0001 11.48 (9.03, 14.59) < 0.0001
Hight TG 2.64 (2.38, 2.92) < 0.0001 2.00 (1.73, 2.31) < 0.0001 1.87 (1.60, 2.19) < 0.0001
High BP 1.87 (1.67, 2.11) < 0.0001 1.78 (1.51, 2.10) < 0.0001 1.85 (1.55, 2.21) < 0.0001
High glucose 2.31 (2.08, 2.54) < 0.0001 1.84 (1.60, 2.12) < 0.0001 1.77 (1.52, 2.06) < 0.0001
Abdominal obesity 2.37 (2.10, 2.67) < 0.0001 1.77 (1.50, 2.09) < 0.0001 1.88 (1.57, 2.25) < 0.0001
Low HDL-C 2.33 (2.10, 2.59) < 0.0001 1.95 (1.69, 2.26) < 0.0001 1.91 (1.63, 2.24) < 0.0001
  1. Model 1: separate models associated each exposure variable with AD with adjustment for age and sex
  2. Model 2: single model including age, sex, smoking, alcohol, physical inactivity, and metabolic syndrome or 5 metabolic syndrome components (high TG, high BP, high glucose, abdominal obesity, low HDL-C)
  3. Model 3: single model including age, sex, smoking, alcohol, physical inactivity, previous stroke, previous cardiac disease, and metabolic syndrome or 5 metabolic syndrome components (high TG, high BP, high glucose, abdominal obesity, low HDL-C)
  4. OR odds ratio, CI confidence interval, MetS metabolic syndrome, TG triglyceride, BP blood pressure, HDL-C high-density lipoprotein cholesterol