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Table 2 Mean changes (95% CI) from baseline in metabolic characteristics by treatment group

From: Combination therapy of flaxseed and hesperidin enhances the effectiveness of lifestyle modification in cardiovascular risk control in prediabetes: a randomized controlled trial

Change from baseline Flax-Hes group (n = 24) Control group (n = 24) P valuea
Weight (kg) − 5.10
(− 6.45, − 3.76)
− 3.10
(− 4.65, − 1.55)
0.048
P valueb < 0.001 0.001  
WC (cm) − 6.75
(− 10.53, − 2.97)
− 3.57
(− 6.43, − 0.73)
0.306
P valueb 0.001 0.017  
Systolic blood pressure − 5.66 (− 10.53, − 1.29) − 1.56 (− 3.57, 0.45) 0.049
P valueb 0.013 0.123  
Diastolic blood pressure − 3.83 (− 8.43, 0.76) − 2.92 (− 5.65, − 0.18) 0.456
P valueb 0.048 0.037  
FBS − 20.35 (− 28.07, − 12.63) − 7.46 (− 12.55, − 2.37) 0.007
P valueb < 0.001 0.007  
Insulin − 3.43 (− 4.86, − 1.99) − 2.46(− 4.21, − 0.72) 0.373
P valueb <0.001 0.008  
HOMA-IR − 1.59 (− 2.37, − 0.83) − 0.73 (− 1.22, − 0.24) 0.055
P valueb < 0.001 0.006  
QUICKI 0.03 (0.01, 0.04) 0.01 (0.004, 0.014) 0.023
P valueb 0.001 0.001  
Triglyceride − 45.30 (− 64.16, − 26.43) − 8.39 (− 43.40, 26.62) 0.020
P valueb < 0.001 0.620  
HDL-C 2.73 (− 1.13, 6.59) 1.30 (− 1.36, 3.96) 0.535
P valueb 0.155 0.317  
LDL-C − 38.35 (− 55.72, − 20.97) − 12.73 (− 24.11, − 1.36) 0.016
P valueb < 0.001 0.030  
hs-CRP − 1044.22 (− 2169.84, 81.39) − 696.05 (− 2642.58, 1250.46) 0.350
P valueb 0.067 0.459  
TNF-α − 6.52 (− 9.83, − 3.21) − 1.95 (− 3.61, − 0.29) 0.015
P valueb 0.001 0.024  
Atherogenic index of plasma (AIP) − 0.16 (− 0.21, − 0.1) − 0.03 (− 0.15, − 0.09) 0.039
P valueb < 0.001 0.539  
Non-HDL/HDL ratio − 1.17
(− 1.67, − 0.66)
− 0.59 (− 1.38, 0.18) 0.042
P valueb < 0.001 0.121  
LDL/HDL ratio − 1.16 (− 1.74, − 0.58) − 0.63 (− 1.14, − 0.11) 0.076
P valueb < 0.001 0.020  
  1. aBased on an ANCOVA model that regressed changes from baseline on treatment group, baseline value of the outcome, age, sex and mean changes in BMI, MET and energy
  2. bPaired t-test
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