Table 2 Mean changes (95% CI) from baseline in metabolic characteristics by treatment group

Weight (kg)

− 5.10

(− 6.45, − 3.76)

− 3.10

(− 4.65, − 1.55)

P value^b

< 0.001

0.001

WC (cm)

− 6.75

(− 10.53, − 2.97)

− 3.57

(− 6.43, − 0.73)

P value^b

0.001

0.017

Systolic blood pressure

− 5.66 (− 10.53, − 1.29)

− 1.56 (− 3.57, 0.45)

P value^b

0.013

0.123

Diastolic blood pressure

− 3.83 (− 8.43, 0.76)

− 2.92 (− 5.65, − 0.18)

P value^b

0.048

0.037

FBS

− 20.35 (− 28.07, − 12.63)

− 7.46 (− 12.55, − 2.37)

P value^b

< 0.001

0.007

Insulin

− 3.43 (− 4.86, − 1.99)

− 2.46(− 4.21, − 0.72)

P value^b

<0.001

0.008

HOMA-IR

− 1.59 (− 2.37, − 0.83)

− 0.73 (− 1.22, − 0.24)

P value^b

< 0.001

0.006

QUICKI

0.03 (0.01, 0.04)

0.01 (0.004, 0.014)

P value^b

0.001

0.001

Triglyceride

− 45.30 (− 64.16, − 26.43)

− 8.39 (− 43.40, 26.62)

P value^b

< 0.001

0.620

HDL-C

2.73 (− 1.13, 6.59)

1.30 (− 1.36, 3.96)

P value^b

0.155

0.317

LDL-C

− 38.35 (− 55.72, − 20.97)

− 12.73 (− 24.11, − 1.36)

P value^b

< 0.001

0.030

hs-CRP

− 1044.22 (− 2169.84, 81.39)

− 696.05 (− 2642.58, 1250.46)

P value^b

0.067

0.459

TNF-α

− 6.52 (− 9.83, − 3.21)

− 1.95 (− 3.61, − 0.29)

P value^b

0.001

0.024

Atherogenic index of plasma (AIP)

− 0.16 (− 0.21, − 0.1)

− 0.03 (− 0.15, − 0.09)

P value^b

< 0.001

0.539

Non-HDL/HDL ratio

− 1.17

(− 1.67, − 0.66)

− 0.59 (− 1.38, 0.18)

P value^b

< 0.001

0.121

LDL/HDL ratio

− 1.16 (− 1.74, − 0.58)

− 0.63 (− 1.14, − 0.11)

P value^b

< 0.001

0.020