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Fig. 7 | Diabetology & Metabolic Syndrome

Fig. 7

From: Long non-coding RNA CDKN2B-AS1 regulates high glucose-induced human mesangial cell injury via regulating the miR-15b-5p/WNT2B axis

Fig. 7

CDKN2B-AS1 regulated DN progression via modulating the miR-15b-5p/WNT2B axis. a, b After si-NC, si-CDKN2B-AS1, si-CDKN2B-AS1 + anti-miR-NC, or si-CDKN2B-AS1 + anti-miR-15b-5p transfection, the levels of WNT2B mRNA and protein in HMCs under HG treatment were detected by qRT-PCR or western blotting, and GADPH was selected as an internal reference. c Schematic diagram showing CDKN2B-AS1 regulated DN development through regulation of the miR-15b-5p/WNT2B axis. The experiments were repeated 3 times, and data were presented as mean ± standard deviation. ****P < 0.0001

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