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Fig. 2 | Diabetology & Metabolic Syndrome

Fig. 2

From: Toxic AGEs (TAGE) theory: a new concept for preventing the development of diseases related to lifestyle

Fig. 2

The TAGE theory of LSRD. Among the various types of AGE structures generated in vivo, TAGE, but not non-toxic AGEs, such as CML, CEL, pentosidine, and pyrraline, appear to play an important role in the pathophysiological processes associated with LSRD. We postulate that non-toxic AGE structures may be physiologically relevant for preventing the potentially damaging consequences of the advanced glycation process. CEL: Nε-(carboxyethyl)lysine; MG-H1: methylglyoxal-hydroimidazolone; MOLD: methylglyoxyl-derived lysine dimer; GOLD: glyoxyl-derived lysine dimer

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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