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Table 3 Insulin dose adjustments based on trend arrows recommendations for adults with T1DM proposed by Ziegler et al

From: Using trend arrows in continuous glucose monitoring systems for insulin adjustment in clinical practice: Brazilian Diabetes Society Position Statement

Rate if change Glucose levels
< 70 70–180 180–250 >250
  Correction factor
Abbott/Roche Dexcom Medtronic   < 25 25– < 50 50– < 75 > 75 < 25 25– < 50 50– < 75 > 75 < 25 25– < 50 50– < 75 > 75
     Recommended changes
  ↑↑ ↑↑↑ CU + 3.5 U + 2.5 U + 1.5 U + 1 U + 4.5 U + 3.5 U + 2.5 U + 1.5 U + 5 U + 4 U + 3 U + 2 U
↑↑ + 2.5 U + 2 U + 1 U + 0.5 U + 3.5 U + 2.5 U + 1.5 U + 1 U + 4 U + 3 U + 2 U + 1.5 U
+ 1.5 U + 1 U + 0.5 U + 0 U + 2.5 U + 1.5 U + 1 U + 0.5 U + 3 U + 2 U + 1.5 U + 1 U
  1 fast-acting CU + 0 U + 0 U + 0 U + 0 U + 0 U + 0 U + 0 U + 0 U + 0 U + 0 U + 0 U + 0 U
2 fast-acting CU − 2.5 U − 1.5 U − 1 U − 0.5 U − 2 U − 1 U − 0.5 U − 0.5 U − 2.5 U − 1 U − 0.5 U − 0 U
↓↓ − 3.5 U − 2.5 U − 1.5 U − 1 U − 3 U − 2 U − 1 U − 1 U − 3.5 U − 2 U − 1 U − 0.5 U
  ↓↓ ↓↓↓ − 4.5 U − 3.5 U − 2.5 U − 1.5 U − 4 U − 3 U − 1.5 U − 1.5 U − 4 U − 2.5 U − 1 U − 0.5 U
  1. Adapted from Ziegler et al. [10]. For individuals with T2D, 0.5 units should be added. For children, 0.5 units should be reduced. Recommendations for SF between 125 and 200 mg/dL and > 200 mg/dL are provided for children [10]