Skip to main content

Table 2 Association between inflammatory mediators and definitive cardiac autonomic neuropathy after adjustment for confounding variables

From: Increased leukotriene B4 plasma concentration in type 2 diabetes individuals with cardiovascular autonomic neuropathy

   TNF IL10 IL1B LTB4
Model 1 Unadjusted P = 0.001 P = 0.002 P = 0.32 P = 0.006
Model 2 Adjusted for sex and age P = 0.18 P = 0.47 P = 0.51 P = 0.006
Model 3 Adjusted for sex, age and body mass index (BMI) P = 0.83 P = 0.32 P = 0.60 P = 0.001
Model 4 Adjusted for sex, age, BMI, and waist circumference (WC) P = 0.17 P = 0.54 P = 0.93 P = 0.016
Model 5 Adjusted for sex, age, BMI, WC, diabetes duration, HbA1c, cholesterol, triglycerides, arterial hypertension, eGFR, and use of ACEi P = 0.67 P = 0.29 P = 0.30 P = 0.013
  1. ACEi: Angiotensin-converting enzyme inhibitors; eGFR: estimated glomerular filtration rate; IL: Interleukin, LTB4: Leukotriene B4; TNF: Tumor necrosis factor. Significantly different P values are shown in italic