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Table 2 Association between inflammatory mediators and definitive cardiac autonomic neuropathy after adjustment for confounding variables

From: Increased leukotriene B4 plasma concentration in type 2 diabetes individuals with cardiovascular autonomic neuropathy

  

TNF

IL10

IL1B

LTB4

Model 1

Unadjusted

P = 0.001

P = 0.002

P = 0.32

P = 0.006

Model 2

Adjusted for sex and age

P = 0.18

P = 0.47

P = 0.51

P = 0.006

Model 3

Adjusted for sex, age and body mass index (BMI)

P = 0.83

P = 0.32

P = 0.60

P = 0.001

Model 4

Adjusted for sex, age, BMI, and waist circumference (WC)

P = 0.17

P = 0.54

P = 0.93

P = 0.016

Model 5

Adjusted for sex, age, BMI, WC, diabetes duration, HbA1c, cholesterol, triglycerides, arterial hypertension, eGFR, and use of ACEi

P = 0.67

P = 0.29

P = 0.30

P = 0.013

  1. ACEi: Angiotensin-converting enzyme inhibitors; eGFR: estimated glomerular filtration rate; IL: Interleukin, LTB4: Leukotriene B4; TNF: Tumor necrosis factor. Significantly different P values are shown in italic
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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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