Table 1 Demographic and general laboratory blood parameters
Parameter | Control | Dapagliflozin 10 mg | P-value | ||
|---|---|---|---|---|---|
Before | After | Con vs Bef | Bef vs Aft | ||
Age (years) | 41.71 ± 6.96 | 54.00 ± 9.61 | – | 0.011 | – |
Men, n (%) | 4 (57.14) | 5 (62.5) | – | 0.833 | – |
Weight (kg) | 71.57 ± 16.15 | 83 ± 9.46 | 66.76 ± 9.79 | 0.674 | 0.360 |
BMI (kg/m2) | 25.16 ± 3.56 | 27.10 ± 2.49 | – | 0.549 | – |
Waist circumference (cm) | 87.86 ± 12.14 | 100.00 ± 7.33 | – | 0.624 | – |
AUCGlu (mmol/L·h) | 20.02 ± 4.15 | 46.73 ± 7.49 | 42.66 ± 7.45 | < 0.001 | 0.066 |
HbA1c (%) | 5.43 ± 0.23 | 7.54 ± 1.42 | – | 0.002 | – |
FBG (mmol/L) | 5.03 ± 0.55 | 7.43 ± 1.58 | 7.43 ± 0.97 | 0.005 | 1.000 |
FINS (μIU/mL) | 9.75 ± 5.05 | 11.10 ± 4.26 | 11.49 ± 4.10 | 0.387 | 0.468 |
SUA (μmol/L) | 283.57 ± 99.93 | 347.75 ± 32.53 | 273.25 ± 43.18 | 0.175 | 0.001 |
TC (mmol/L) | 4.98 ± 0.57 | 5.35 ± 0.83 | 5.34 ± 0.90 | 0.376 | 0.947 |
TG (mmol/L) | 1.69 ± 0.87 | 2.10 ± 0.98 | 1.71 ± 0.74 | 0.441 | 0.135 |
HDL-c (mmol/L) | 1.36 ± 0.44 | 1.05 ± 0.13 | 1.09 ± 0.16 | 0.144 | 0.191 |
LDL-c (mmol/L) | 3.04 ± 0.51 | 3.57 ± 0.79 | 3.72 ± 1.01 | 0.186 | 0.282 |