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Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: LncRNA KCNQ1OT1 affects cell proliferation, apoptosis and fibrosis through regulating miR-18b-5p/SORBS2 axis and NF-ĸB pathway in diabetic nephropathy

Fig. 3

Silencing of SORBS2 repressed proliferation and facilitated apoptosis in high glucose-induced HGMCs and HRGECs. High glucose-induced HGMCs and HRGECs were transfected with si-SORBS2. a, b The mRNA and protein levels of SORBS2 were detected by qRT-PCR and western blot. c, d proliferation of HGMCs and HRGECs was determined by MTT assay. e apoptosis of HGMCs and HRGECs was determined by flow cytometry assay. f The expression of fibrosis-related proteins was measured by western blot assay. N = 3, *P < 0.05

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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