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Table 1 The serum ucOC levels and insulin secretion indices in the NGT, IGM and DM groups

From: Undercarboxylated osteocalcin correlates with insulin secretion in Japanese individuals with diabetes

  NGT (n = 25) IGM (n = 25) DM (n = 25) P
ucOC (ng/mL) 4.3 (3.1, 5.2) 4.0 (3.3, 6.6) 4.0 (2.6, 5.8) 0.9411
Ln-ucOC 1.407 ± 0.516 1.383 ± 0.817 1.389 ± 0.606 0.9914
AUCins/gluc (pmol/mmol) 29.7 (20.4, 51.4) 32.4 (19.2, 46.0) 22.0 (13.3, 31.7) 0.0295
Ln- AUCins/gluc 3.452 ± 0.593 3.465 ± 0.573 3.046 ± 0.545*,** 0.0164
ISSI-2 181.9 (164.8, 219.5) 119.8* (103.3, 158.3) 77.7*,** (59.4, 85.9)  < 0.0001
Ln-ISSI-2 5.266 ± 0.314 4.869 ± 0.351* 4.286 ± 0.334*,**  < 0.0001
  1. Median values are shown. The 25th percentile and 75th percentile values are shown in parenthesis
  2. ucOC undercarboxylated osteocalcin, AUCins/gluc the ratio of the area-under-the-insulin-curve to the area-under-the-glucose-curve, ISS1-2 the component measures of the insulin secretion-sensitivity index-2
  3. * P < 0.01 vs NGT; ** P < 0.01 vs IGM