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Table 1 The serum ucOC levels and insulin secretion indices in the NGT, IGM and DM groups

From: Undercarboxylated osteocalcin correlates with insulin secretion in Japanese individuals with diabetes

 

NGT (n = 25)

IGM (n = 25)

DM (n = 25)

P

ucOC (ng/mL)

4.3 (3.1, 5.2)

4.0 (3.3, 6.6)

4.0 (2.6, 5.8)

0.9411

Ln-ucOC

1.407 ± 0.516

1.383 ± 0.817

1.389 ± 0.606

0.9914

AUCins/gluc (pmol/mmol)

29.7 (20.4, 51.4)

32.4 (19.2, 46.0)

22.0 (13.3, 31.7)

0.0295

Ln- AUCins/gluc

3.452 ± 0.593

3.465 ± 0.573

3.046 ± 0.545*,**

0.0164

ISSI-2

181.9 (164.8, 219.5)

119.8* (103.3, 158.3)

77.7*,** (59.4, 85.9)

 < 0.0001

Ln-ISSI-2

5.266 ± 0.314

4.869 ± 0.351*

4.286 ± 0.334*,**

 < 0.0001

  1. Median values are shown. The 25th percentile and 75th percentile values are shown in parenthesis
  2. ucOC undercarboxylated osteocalcin, AUCins/gluc the ratio of the area-under-the-insulin-curve to the area-under-the-glucose-curve, ISS1-2 the component measures of the insulin secretion-sensitivity index-2
  3. * P < 0.01 vs NGT; ** P < 0.01 vs IGM