Therapeutic effects of different doses of prebiotic (isolated from Saccharomyces cerevisiae) in comparison to n-3 supplement on glycemic control, lipid profiles and immunological response in diabetic rats

Table 2 Histopathological scores of the pancreas of streptozotocin-induced diabetic rats (70 mg/kg) treated with different doses of yeast β-glucan

Treatment	Pancreatic islet cell number reduction score
Treatment	Normal (−)	Mild (+)	Moderate (++)	Severe (+++)
Control	5	0	0	0	+
n-3	0	3	3	1	*
0 mg	0	5	2	0	*
10 mg	0	4	2	1	*
20 mg	0	4	2	1	*
40 mg	0	4	3	0	*

*No statistically significant differences among diabetic groups according to the Kruskal-Wallis test (p > 0.05). + Significant difference in relation to diabetic groups according to the Kruskal-Wallis test (p < 0.05)

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