Skip to main content
Fig. 5 | Diabetology & Metabolic Syndrome

Fig. 5

From: Long non-coding RNA cancer susceptibility candidate 2 (CASC2) alleviates the high glucose-induced injury of CIHP-1 cells via regulating miR-9-5p/PPARγ axis in diabetes nephropathy

Fig. 5

CASC2 alleviated the HG-induced podocytes injury by increasing PPARγ. The HG-treated CIHP-1 cells were transfected with Vector, CASC2, CASC2 + si-NC and si-PPARγ, respectively. a PPARγ protein expression was examined by western blot. b, c Cell viability and apoptosis were determined by CCK-8 assay and Flow cytometry, respectively. d, e The expression levels of BCL-2, Cleaved-caspase-3, LC3-II, LC3-I and Beclin 1 were checked by western blot assay. *P < 0.05

Back to article page

Diabetology & Metabolic Syndrome

ISSN: 1758-5996

Contact us