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Fig. 3 | Diabetology & Metabolic Syndrome

Fig. 3

From: Long non-coding RNA cancer susceptibility candidate 2 (CASC2) alleviates the high glucose-induced injury of CIHP-1 cells via regulating miR-9-5p/PPARγ axis in diabetes nephropathy

Fig. 3

CASC2 regulated the HG-induced podocytes injury via targeting miR-9-5p. The HG-treated CIHP-1 cells were divided into four groups: Vector, CASC2, CASC2 + miR-NC and HG + miR-9-5p. a The expression of miR-9-5p was examined by qRT-PCR. b, c Cell viability and apoptosis were evaluated by CCK-8 assay and flow cytometry, respectively. d, e The expression levels of apoptosis-related proteins BCL-2 and Cleaved-caspase-3 and autophagy related proteins LC3-II, LC3-I and Beclin 1 were detected by western blot assay. *P < 0.05

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