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Table 4 Distribution of clinical parameters of participants in different tertiles based on serum concentrations of asprosin in all subjects

From: Serum concentration of asprosin in new-onset type 2 diabetes

Variable

T1

T2

T3

P-value

Asprosin (ng/mL)

2.18 (0.4)

3.65 (1.58)

8.04 (1.74)

< 0.001

Age (year)

53 (13)

52 (8)

53 (8)

0.822

BMI (kg/m2)

25.79 (1.82)

26.75 (3)

28.38 (2.98)

< 0.001

FBG (mg/dL)

83.5 (15)

100 (36)

209 (83)

< 0.001

Insulin (mIU/L)

7.7 (5.01)

7.5 (5.45)

10.55 (4.18)

< 0.001

HbA1c (%)

5.50 (0.7)

5.73 (1.72)

8.99 (2.09)

< 0.001

TC (mg/dL)

198.5 (61)

194 (63)

197 (41)

0.403

TAG (mg/dL)

136 (87)

153 (79)

223 (145)

< 0.001

HDL-C (mg/dL)

42.5 (18)

43 (15)

52 (17)

< 0.001

LDL-C (mg/dL)

124.5 (49)

125 (56)

96 (21)

0.002

LDL-C/HDL-C

3.11 (1.69)

2.85 (1.74)

2.04 (0.4)

< 0.001

TC/HDL-C

4.65 (2.06)

4.19 (1.43)

3.98 (0.64)

0.052

TAG/HDL-C

3.56 (2.26)

3.52 (1.74)

4.41 (3.85)

0.041

HOMA-IR

0.99 (0.76)

0.99 (0.86)

1.83 (0.75)

< 0.001

HOMA-β

87 (54.92)

64.85 (32.32)

25.4 (19.50)

< 0.001

HOMA-S

99.85 (93.12)

101.2 (97.85)

54.60 (20.75)

< 0.001

QUICKI

0.36 (0.05)

0.35 (0.06)

0.29 (0.01)

< 0.001

  1. Data are shown as median (IQR). Kruskal–Wallis was performed. One way ANOVA test was performed for TC
  2. BMI body mass index, FBG fasting blood sugar, HbA1c hemoglobin A1c, TC total cholesterol, TAG triacylglycerol, HDL-C HDL cholesterol, LDL-C LDL cholesterol, HOMA-IR homeostatic model assessment of insulin resistance, HOMA-β, QUICKI quantitative insulin sensitivity check index, triacylglycerol (TAG) and total cholesterol/HDL cholesterol (TC/HDL-C) ratio