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Table 4 Distribution of clinical parameters of participants in different tertiles based on serum concentrations of asprosin in all subjects

From: Serum concentration of asprosin in new-onset type 2 diabetes

Variable T1 T2 T3 P-value
Asprosin (ng/mL) 2.18 (0.4) 3.65 (1.58) 8.04 (1.74) < 0.001
Age (year) 53 (13) 52 (8) 53 (8) 0.822
BMI (kg/m2) 25.79 (1.82) 26.75 (3) 28.38 (2.98) < 0.001
FBG (mg/dL) 83.5 (15) 100 (36) 209 (83) < 0.001
Insulin (mIU/L) 7.7 (5.01) 7.5 (5.45) 10.55 (4.18) < 0.001
HbA1c (%) 5.50 (0.7) 5.73 (1.72) 8.99 (2.09) < 0.001
TC (mg/dL) 198.5 (61) 194 (63) 197 (41) 0.403
TAG (mg/dL) 136 (87) 153 (79) 223 (145) < 0.001
HDL-C (mg/dL) 42.5 (18) 43 (15) 52 (17) < 0.001
LDL-C (mg/dL) 124.5 (49) 125 (56) 96 (21) 0.002
LDL-C/HDL-C 3.11 (1.69) 2.85 (1.74) 2.04 (0.4) < 0.001
TC/HDL-C 4.65 (2.06) 4.19 (1.43) 3.98 (0.64) 0.052
TAG/HDL-C 3.56 (2.26) 3.52 (1.74) 4.41 (3.85) 0.041
HOMA-IR 0.99 (0.76) 0.99 (0.86) 1.83 (0.75) < 0.001
HOMA-β 87 (54.92) 64.85 (32.32) 25.4 (19.50) < 0.001
HOMA-S 99.85 (93.12) 101.2 (97.85) 54.60 (20.75) < 0.001
QUICKI 0.36 (0.05) 0.35 (0.06) 0.29 (0.01) < 0.001
  1. Data are shown as median (IQR). Kruskal–Wallis was performed. One way ANOVA test was performed for TC
  2. BMI body mass index, FBG fasting blood sugar, HbA1c hemoglobin A1c, TC total cholesterol, TAG triacylglycerol, HDL-C HDL cholesterol, LDL-C LDL cholesterol, HOMA-IR homeostatic model assessment of insulin resistance, HOMA-β, QUICKI quantitative insulin sensitivity check index, triacylglycerol (TAG) and total cholesterol/HDL cholesterol (TC/HDL-C) ratio