Association between neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and diabetic retinopathy among diabetic patients without a related family history

Table 1 Baseline characteristics of the DR and NDR groups

Variable	DR group N = 264	NDR group N = 206	P
Gender (male/female)	131/133	146/60	0.000**
Hypertension (no/yes)	95/169	108/98	0.000**
Smoking (no/yes)	168/96	107/99	0.007*
Drinking (no/yes)	180/84	119/87	0.013*
Sulfonylureas (no/yes)	147/117	110/96	0.344
Biguanides (no/yes)	129/135	95/110	0.327
Insulin (no/yes)	127/137	108/98	0.201
Age (years)	56.48 ± 9.86	55.44 ± 11.27	0.295
NLR	2.36 ± 1.16	1.97 ± 1.06	0.000**
MLR (*10)	2.28 ± 1.03	2.34 ± 1.28	0.628
PLR (*0.1)	11.62 ± 4.55	10.56 ± 4.45	0.012*
Neutrophils (*10⁹/L)	4.25 ± 1.31	3.72 ± 1.22	0.000**
Lymphocytes (*10⁹/L)	1.98 ± 0.64	2.11 ± 0.67	0.031*
Monocytes (*10⁹/L)	0.42 ± 0.15	0.44 ± 0.15	0.097
Platelets (*10⁹/L)	213.84 ± 69.19	203.90 ± 54.66	0.092
Diabetes course (month)	122.86 ± 87.38	66.16 ± 66.25	0.000**
BMI (kg/m²)	24.12 ± 3.25	24.62 ± 3.14	0.090
FPG (mmol/L)	9.60 ± 3.79	8.80 ± 3.27	0.019 *
HbA1c (%)	9.96 ± 2.45	9.68 ± 2.66	0.246
WBC (*10⁹/L)	6.83 ± 1.65	6.45 ± 1.50	0.010*
Hb (g/L)	136.25 ± 19.33	153.20 ± 15.70	0.000**
BUN (mmol/L)	7.07 ± 7.82	5.32 ± 1.64	0.000**
Scr (mmol/L)	84.21 ± 46.63	69.14 ± 17.87	0.000**
TG (mg/dL)	3.02 ± 2.37	2.29 ± 1.99	0.000**
TC (mg/dL)	4.73 ± 2.09	4.79 ± 1.13	0.694
HDL-C (mg/dL)	1.16 ± 0.33	1.12 ± 0.57	0.434
LDL-C (mg/dL)	3.11 ± 0.98	2.97 ± 0.88	0.110

DR diabetic retinopathy, NDR non-diabetic retinopathy, NLR neutrophil-to-lymphocyte ratio, MLR monocyte-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, BMI body mass index, FPG fasting plasma glucose, HbA1c glycated hemoglobin A1c, WBC white blood cell, Hb hemoglobin, BUN blood urea nitrogen,Scr serum creatinine,TG triglycerides, TC total cholesterol, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol
*P < 0.05, **P < 0.01

ISSN: 1758-5996