Table 1 Demographic and clinical characteristic of study subjects
From: Association of [1H]-MRS quantified liver fat content with glucose metabolism status
Parameters | nT2DM (n = 141) | PDM (n = 48) | NC (n = 53) | p value |
|---|---|---|---|---|
Age (year) | 50.8 ± 10.1 | 49.7 ± 13.0 | 47.0 ± 8.0 | 0.078 |
Gender (female/male) | 69/72 | 23/25 | 25/28 | 0.974 |
BMI (kg/cm2) | 26.5 (25.4, 27.7) | 25.7 (24.1, 26.8) | 23.6 (22.1, 24.6) | 0.000 |
WC (cm) | 88.72 ± 9.94 | 91.87 ± 9.00 | 83.08 ± 7.81 | 0.000 |
HIP (cm) | 92.06 ± 8.14 | 98.63 ± 8.39 | 95.19 ± 6.96 | 0.000 |
WHR | 0.95 (0.92, 1.04) | 0.90 (0.88, 0.94) | 0.86 (0.83, 0.88) | 0.000 |
SBP (mmHg) | 135 ± 16 | 136 ± 16 | 125 ± 14 | 0.001 |
DBP (mmHg) | 83 ± 11 | 83 ± 11 | 77 ± 10 | 0.001 |
Urea Nitrogen (mmol/l) | 5.10 ± 1.48 | 5.09 ± 1.56 | 4.82 ± 1.18 | 0.464 |
Cr (umol/l) | 57.97 ± 14.37 | 59.98 ± 14.20 | 62.85 ± 13.80 | 0.101 |
UA (umol/l) | 342.04 ± 63.36 | 319.25 ± 75.46 | 294.15 ± 54.47 | 0.000 |
TBIL(umol/l) | 15.9 (13.2, 21.2) | 15.7 (11.5, 20.5) | 13.6 (11.3, 16.6) | 0.074 |
DBIL(umol/l) | 4.2 (3.3, 5.5) | 3.7 (2.7, 5.1) | 4.2 (3.0, 5.1) | 0.540 |
IBIL(umol/l) | 11.9 (9.6, 16.3) | 12.0 (8.4, 15.1) | 9.6 (7.9, 12.5) | 0.045 |
ALP (U/l) | 76 ± 21 | 76 ± 21 | 71 ± 22 | 0.289 |
AST (U/l) | 20 (16, 28) | 24 (18, 29) | 19 (16, 24) | 0.019 |
ALT (U/l) | 35 (32, 38) | 31 (26, 36) | 18 (13, 27) | 0.000 |
GGT (U/l) | 36 (26, 54) | 34 (19, 68) | 23 (16, 34) | 0.007 |
LDH (U/l) | 166 ± 33 | 189 ± 38 | 184 ± 32 | 0.000 |
TG (mmol/l) | 2.4 ± 0.6 | 1.9 ± 0.7 | 1.4 ± 0.6 | 0.000 |
TC (mmol/l) | 5.4 ± 0.3 | 4.8 ± 0.2 | 4.1 ± 0.4 | 0.000 |
HDL-C (mmol/l) | 1.4 ± 0.3 | 1.5 ± 0.3 | 1.6 ± 0.4 | 0.000 |
LDL-C (mmol/l) | 3.3 ± 0.4 | 2.9 ± 0.7 | 2.2 ± 0.2 | 0.000 |
VLDL-C (mmol/l) | 0.4 (0.3, 0.6) | 0.3 (0.2, 0.5) | 0.2 (0.1, 0.4) | 0.003 |
ApoB (g/l) | 0.9 (0.7, 1.1) | 0.9 (0.7, 1.0) | 0.9 (0.8, 1.0) | 0.403 |
ApoA1 (g/l) | 1.1 ± 0.2 | 1.2 ± 0.2 | 1.2 ± 0.2 | 0.000 |
FPG (mmol/l) | 7.44 ± 1.07 | 5.54 ± 0.65 | 4.84 ± 0.62 | 0.000 |
2hPG (mmol/l) | 16.90 (14.00, 17.88) | 8.93 (8.05, 9.75) | 6.05 (5.34, 6.71) | 0.000 |
Fasting Insulin (mU/l) | 6.31 (5.24, 8.47) | 7.77 (6.05, 8.70) | 6.63 (5.54, 8.26) | 0.021 |
HOMA-IR | 2.20 (1.73, 2.78) | 1.82 (1.45, 2.22) | 1.44 (1.19, 1.86) | 0.000 |
HOMA-β | 32.89 (24.32, 45.60) | 81.09 (59.16, 109.50) | 117.11 (74.55, 158.77) | 0.000 |
Matsuda ISI | 93.38 ± 38.31 | 78.76 ± 24.14 | 114.64 ± 44.28 | 0.000 |