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Table 1 Demographic and clinical characteristic of study subjects

From: Association of [1H]-MRS quantified liver fat content with glucose metabolism status

ParametersnT2DM
(n = 141)
PDM
(n = 48)
NC
(n = 53)
p value
Age (year)50.8 ± 10.149.7 ± 13.047.0 ± 8.00.078
Gender (female/male)69/7223/2525/280.974
BMI (kg/cm2)26.5 (25.4, 27.7)25.7 (24.1, 26.8)23.6 (22.1, 24.6)0.000
WC (cm)88.72 ± 9.9491.87 ± 9.0083.08 ± 7.810.000
HIP (cm)92.06 ± 8.1498.63 ± 8.3995.19 ± 6.960.000
WHR0.95 (0.92, 1.04)0.90 (0.88, 0.94)0.86 (0.83, 0.88)0.000
SBP (mmHg)135 ± 16136 ± 16125 ± 140.001
DBP (mmHg)83 ± 1183 ± 1177 ± 100.001
Urea Nitrogen (mmol/l)5.10 ± 1.485.09 ± 1.564.82 ± 1.180.464
Cr (umol/l)57.97 ± 14.3759.98 ± 14.2062.85 ± 13.800.101
UA (umol/l)342.04 ± 63.36319.25 ± 75.46294.15 ± 54.470.000
TBIL(umol/l)15.9 (13.2, 21.2)15.7 (11.5, 20.5)13.6 (11.3, 16.6)0.074
DBIL(umol/l)4.2 (3.3, 5.5)3.7 (2.7, 5.1)4.2 (3.0, 5.1)0.540
IBIL(umol/l)11.9 (9.6, 16.3)12.0 (8.4, 15.1)9.6 (7.9, 12.5)0.045
ALP (U/l)76 ± 2176 ± 2171 ± 220.289
AST (U/l)20 (16, 28)24 (18, 29)19 (16, 24)0.019
ALT (U/l)35 (32, 38)31 (26, 36)18 (13, 27)0.000
GGT (U/l)36 (26, 54)34 (19, 68)23 (16, 34)0.007
LDH (U/l)166 ± 33189 ± 38184 ± 320.000
TG (mmol/l)2.4 ± 0.61.9 ± 0.71.4 ± 0.60.000
TC (mmol/l)5.4 ± 0.34.8 ± 0.24.1 ± 0.40.000
HDL-C (mmol/l)1.4 ± 0.31.5 ± 0.31.6 ± 0.40.000
LDL-C (mmol/l)3.3 ± 0.42.9 ± 0.72.2 ± 0.20.000
VLDL-C (mmol/l)0.4 (0.3, 0.6)0.3 (0.2, 0.5)0.2 (0.1, 0.4)0.003
ApoB (g/l)0.9 (0.7, 1.1)0.9 (0.7, 1.0)0.9 (0.8, 1.0)0.403
ApoA1 (g/l)1.1 ± 0.21.2 ± 0.21.2 ± 0.20.000
FPG (mmol/l)7.44 ± 1.075.54 ± 0.654.84 ± 0.620.000
2hPG (mmol/l)16.90 (14.00, 17.88)8.93 (8.05, 9.75)6.05 (5.34, 6.71)0.000
Fasting Insulin (mU/l)6.31 (5.24, 8.47)7.77 (6.05, 8.70)6.63 (5.54, 8.26)0.021
HOMA-IR2.20 (1.73, 2.78)1.82 (1.45, 2.22)1.44 (1.19, 1.86)0.000
HOMA-β32.89 (24.32, 45.60)81.09 (59.16, 109.50)117.11 (74.55, 158.77)0.000
Matsuda ISI93.38 ± 38.3178.76 ± 24.14114.64 ± 44.280.000
  1. ApoA1 Apolipoprotein A1, ApoB Apolipoprotein B, ALP alkaline phosphatase, AST aspartate aminotransferase, ALT alanine transaminase, BMI body mass index, Cr creatine, DBIL direct bilirubin, DBP diastolic blood pressure, FPG fasting plasma glucose, GGT γ-glutamyltransferase, HOMA-IR homeostatic model assessment of insulin resistance, HOMA-β homeostatic model assessment for β-cell function, HDL-C high-density lipoprotein cholesterol, IBIL indirect bilirubin, LDH lactate dehydrogenase, LDL-C low-density lipoprotein cholesterol, nT2DM newly diagnosed type 2 diabetes mellitus, NC normal control, PDM prediabetes mellitus, SBP systolic blood pressure, TC total cholesterol, TG triglycerides, TBIL total bilirubin, UA uric acid, VLDL-C very low-density lipoprotein cholesterol, WC waist circumference, WHR waist-to-hip ratio