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Table 1 Maternal and pregnancy characteristics according to glucose status

From: Maternal factors associated with hyperglycemia in pregnancy and perinatal outcomes: a Brazilian reference center cohort study

Characteristics

GDM

MGH

ND

p value*

N (%)

N (%)

N (%)

Age ≥ 25 years

181 (87.86)a

108 (81.20)a

143 (62.72)b

<0.0001

Prenatal visits < 6

24 (13.04)a

10 (9.17)ab

11 (5.26)a

0.0264

Multiparity (≥ 2)

173 (86.93)a

110 (85.27)a

143 (64.71)b

<0.0001

Without partner

14 (7.07)a

19 (14.73)b

36 (16.36)b

0.0120

Nonwhite ethnicity

73 (36.87)

47 (37.01)

78 (35.29)

0.9270

Smoking

41 (19.81)

27 (20.30)

34 (14.91)

0.2995

Nonexercise/sedentarism

107 (54.04)a

86 (67.19)a

160 (74.42)b

< 0.0001

Not working/housewife

116 (58.88)

72 (57.14)

106 (48.85)

0.0966

Family history of DM (1st degree)

95 (47.50)a

54 (41.54)a

59 (26.94)b

< 0.0001

Hypertension

75 (36.23)a

55 (41.67)ab

62 (27.43)a

0.0161

Prepregnancy BMI ≥ 25 kg/m2

169 (87.56)a

95 (74.80)b

124 (56.88)c

< 0.0001

Excessive weight gain

77 (42.54)

43 (37.72)

90 (43.48)

0.5885

OGTT-100 g (N = 220; mg/dL)a

 FPG ≥ 95

39 (54.93)a

6 (9.09)b

0 (0.00)b

<0.0001

 1 h ≥ 180

50 (70.42)a

3 (4.55)b

1 (1.20)b

< 0.0001

 2 h ≥ 165

52 (73.24)a

4 (6.06)b

2 (2.41)b

< 0.0001

 3 h ≥ 140

41 (57.75)a

4 (6.06)b

0 (0.00)b

< 0.0001

OGTT-75 g (N = 333; mg/dL)b

 FPG ≥ 92

77 (60.16)a

0 (0.00)b

0 (0.00)b

< 0.0001

 1 h ≥ 180

64 (51.20)a

0 (0.00)b

0 (0.00)b

< 0.0001

 2 h ≥ 153

63 (50.00)a

0 (0.00)b

0 (0.00)b

< 0.0001

GP mean ≥ 120 mg/dL (at diagnosis)

14 (6.97)a

2 (1.54)b

1 (0.44)b

0.0003

HbA1c ≥ 6.5% (at birth)

21 (10.40)a

7 (5.51)a

2 (0.97)b

0.0002

HbA1c ≥ 6.0% (at birth)

57 (28.22)a

27 (21.26)a

15 (7.28)b

< 0.0001

  1. GDM gestational diabetes mellitus, MGH mild gestational hyperglycemia, ND nondiabetes, DM diabetes mellitus, BMI body mass index, OGTT oral glucose tolerance test, FPG fasting plasma glucose, 1 h 1-h postload, 2 h 2-h postload, 3 h 3-h postload, GP glucose profile, HbA1c glycate hemoglobin
  2. * Chi squared or Fisher’s exact tests; for each specific variable, values followed by the same letter (a, b or c) are not significantly different (p ≥ 0.05); significant values were highlighted in italic
  3. aMissed = 6; bMissed = 10