Endurance exercise training restores diabetes-induced alteration in circulating Glycosylphosphatidylinositol-specific phospholipase D levels in rats

Table 1 The morphometric, metabolic, hormonal and biochemical measurements of the rats following 14 weeks in the groups

Variables	SC	SD	TD
Body weight (g)	231 ± 17	235 ± 24	211 ± 44
Length (cm)	22 ± 0.74	22 ± 0.85	21 ± 1.5
BMI	0.477 ± 0.02	0.489 ± 0.07	0.474 ± 0.03
FBS (mmol/L)	6.14 ± 0.58	21.72 ± 1.24^a	16.92 ± 3.35^{a, b}
2hOGTT (mmol/L)	6.72 ± 0.64	44.21 ± 2.61^a	30.61 ± 2.21^{a, b}
AUC glucose (mmol/L × 120 min)	873 ± 78	4937 ± 264^a	3703 ± 115^{a, b}
FIns (μU/mL)	31.56 ± 3.4	8.73 ± 3.42^a	14.7 ± 3.97^{a, b}
GPLD1 (ng/mL)	33.41 ± 3.65	48.78 ± 2.78^a	36.37 ± 4.06^b
GPC-4 (ng/mL)	2.13 ± 0.19	2.3 ± 0.33	2.07 ± 0.37

Values are expressed as mean ± SD, and n = 12 for all groups
SC sedentary control group, SD sedentary diabetic group, TD trained diabetic group, BMI body mass index, FBS fasting blood sugar, FIns fasting serum insulin, 2hOGTT 2 h post-glucose load blood glucose, AUC glucose, area under the curve of glucose, GPLD1 glycosylphosphatidylinositol-specific phospholipase D, GPC-4 glypican-4.
^ap < 0.001 vs. SC; ^bp < 0.001 vs. SD

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