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Table 3 Linear correlation and multiple regression analysis of variables associated with circulating Nrg4 in study subjects

From: Changes of circulating neuregulin 4 and its relationship with 25-hydroxy vitamin D and other diabetic vascular complications in patients with diabetic peripheral neuropathy

Variable Simple Multiple
R P-value Adjusted r Adjusted P-value β Standardized β P-value
Sex 0.125 0.110    
Age 0.075 0.340    
BMI − 0.165 0.035    
SBP 0.115 0.142 0.125 0.114 0.021 0.150 0.034
DBP 0.083 0.290 0.104 0.190    
FBG − 0.123 0.116 − 0.077 0.329    
PBG − 0.032 0.680 − 0.017 0.834    
HbA1c 0.035 0.653 0.031 0.697    
FIns 0.010 0.894 0.006 0.937    
HOMA-IR − 0.061 0.440 − 0.032 0.690    
TC 0.110 0.159 0.105 0.184    
TG − 0.034 0.661 0.042 0.598    
HDL-C 0.148 0.059 0.109 0.169    
LDL-C 0.117 0.136 0.113 0.155 0.245 0.149 0.035
UACR 0.122 0.120 0.103 0.19    
eGFR − 0.078 0.322 − 0.076 0.337    
Scr − 0.005 0.947 0.058 0.469    
25(OH)D 0.194 0.013 0.240 0.002 0.070 0.220 0.002
ABI − 0.011 0.893 0.000 0.997    
VPT − 0.412 0.000 − 0.360 0.000 − 0.059 − 0.372 0.000
DPN − 0.276 0.000 − 0.218 0.005    
VPT > 25 V − 0.506 0.000 − 0.433 0.000    
Abnormal prickingsensation − 0.078 0.322 0.130 0.100    
Abnormal nylon monofilament 0.017 0.832 − 0.079 0.319    
Reflex abnormalities − 0.116 0.139 − 0.067 0.401    
DN 0.000 0.999 0.045 0.571    
DR 0.003 0.972 0.014 0.864    
PAD 0.055 0.485 0.010 0.896    
  1. In multiple linear stepwise regression analysis, values included for analysis in nT2DM patients were sex, age, BMI, SBP, DBP, FBG, PBG, HbA1C, FIns, HOMA-IR, TG, TC, HDL-C, LDL-C, UACR, eGFR, Scr, 25(OH)D, ABI, and VPT