Fig. 1From: Changes of circulating neuregulin 4 and its relationship with 25-hydroxy vitamin D and other diabetic vascular complications in patients with diabetic peripheral neuropathyROC analysis of circulating Nrg4 and 25(OH)D to indicate DPN for nT2DM patients. For circulating Nrg4, AUC = 0.660; 95% CI 0.576–0.744; P = 0.000; identified Nrg4 cutoff value = 3.03 ng/ml; Youden index = 0.268; sensitivity: 55.7%; specificity: 71.1%; For circulating 25(OH)D, AUC = 0.635; 95% CI 0.551–0.720; P = 0.003; identified 25(OH)D cutoff value = 16.491 ng/ml; Youden index = 0.286; sensitivity: 52.3%; specificity: 76.3%Back to article page