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Table 4 Adjusted changes in glycemic indices, lipid profiles and anthropometric indices in each group

From: The effect of omega-3 and vitamin D co-supplementation on glycemic control and lipid profiles in reproductive-aged women with pre-diabetes and hypovitaminosis D: a randomized controlled trial

Variables

Group 1

Placebo group (n = 42)

Group 2

Omega 3 group (n = 42)

Group 3

Vitamin D group (n = 42)

Group 4

Vitamin + Omega 3 group (n = 42)

P value¥

ηp2¥

Time

Time*

group

interaction

time

Time*

group

interaction

Vitamin D

− 4.49 (5.03)

− 2.38 (5.28)

8.27 (7.77)

9.68 (7.34)#

< .001*

< .001*

.15

.49

FBS (mg/dL)

2.60 (6.59)

− 6.64 (5.14)

− 3.56 (7.11)

− 9.37 (6.4)ǁ

< .001*

< .001*

.3

.33

Insulin (µIU/mL)

3.06 (3.69)

− 1.80 (2.16)

1.92 (3.91)

− 2.61 (1.68)ǁ

.13

< .001*

.002

.38

HOMA-IR

0.83 (1.05)

− 0.58 (0.51)

0.40 (1.05)

− 0.85 (0.48)

.04*

< .001*

.004

.42

HOMA-B

0.28 (0.53)

− 0.002 (0.42)

0.27 (0.4)

− 0.04 (0.31)ǁ

< .001*

< .001*

.08

.19

Triglycerides (mg/dL)

10.81 (54.27)

− 15.48 (40.02)

3.27 (56.55)

− 22.32 (34.58)

< .001*

< .001*

.01

.07

Total-cholesterol (mg/dL)

− 4.21 (22.71)

− 14.29 (26.8)

− 10.23 (29.89)

− 22.74 (29.7)

< .001*

< .001*

.18

.006

HDL-C (mg/dL)

− 0.32 (3.74)

0.82 (5.35)

0.4 (5.15)

1.29 (5.68)ǁ

< .001*

.004*

.01

.01

LDL-C (mg/dL)

− 4.12 (20.58)

− 11.53 (25.52)

− 10.29 (26.40)

− 19.04 (29.03)

< .001*

< .001*

.16

.04

Weight

0.31 (1.03)

− 0.06 (1.42)

0.06 (1.27)

− 0.36 (1.65)ǁ

.77

< .001*

0

.03

BMI

− 0.002 (0.54)

− 0.07 (0.81)

− 0.036 (0.63)

− 0.05 (0.68)

.04

.63

.004

.002

Waist circumference

− 0.01 (1.7)

− 0.84 (1.77)

− 0.43 (1.8)

− 1.15 (2.23)ǁ

< .001*

< .001*

.09

.05

  1. All values are means (SDs)
  2. *P value is significant
  3. ¥ Obtain from two way repeated measures ANOVA after adjusting for covariates
  4. # Significant difference with group 1 and 2
  5. ǁ Significant difference with and other 3 groups
  6. (¥, ǁ, #) Obtain from Two way repeated measures ANOVA with Bonferroni correction
  7. ηp2 (partial eta squared) = 0.14 or more are large effects, 0.06 to 0.14 are medium effects and Less than 0.6 are small effects