Table 3 Subgroup analysis of the association between MetS and OA
Subgroup | No of studies | OR (95% CI) | p value heterogeneity | I2(%) |
|---|---|---|---|---|
MetS predicting OA | ||||
 Ethnicity | ||||
  Asian | 4 | 1.40 (1.03, 1.90) | 0.001 | 79.1 |
  European | 7 | 1.49 (1.29, 1.71) | 0.017 | 53.7 |
 Study design | ||||
  Cohort study | 4 | 1.76 (1.29, 2.42) | 0.000 | 79.3 |
  Cross-sectional study | 7 | 1.32 (1.21, 1.44) | 0.395 | 4.8 |
 Location | ||||
  Knee | 9 | 1.56 (1.31, 1.87) | 0.000 | 74.3 |
  Hand | 4 | 1.44 (1.25, 1.66) | 0.485 | 0 |
  Hip | 2 | 1.15 (0.94, 1.41) | 0.504 | 0 |
 MetS criteria | ||||
  NCEP ATPIII | 8 | 1.38 (1.23, 1.56) | 0.075 | 39.9 |
  IDF | 1 | 1.52 (0.95, 2.43) | 0.001 | 90.2 |
OA predicting MetS | ||||
 Gender | ||||
  Male | 3 | 0.84 (0.61, 1.16) | 0.248 | 28.2 |
  Female | 3 | 2.34 (1.54, 3.56) | 0.708 | 0 |
 MetS criteria | ||||
  NCEP ATPIII | 2 | 1.12 (0.65, 1.93) | 0.01 | 78.3 |
  Modified criteria | 2 | 4.12 (1.48, 11.42) | 0.901 | 0 |
  Japan criteria | 2 | 1.64 (0.60, 4.50) | 0.020 | 74.3 |
 Location | ||||
  Knee | 6 | 1.55 (1.02, 2.26) | 0.000 | 78.9 |
  Hand | 1 | 2.67 (1.15, 6.19) | 0.000 | 0 |