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Fig. 4 | Diabetology & Metabolic Syndrome

Fig. 4

From: Potential therapeutic effects of endothelial cells trans-differentiated from Wharton’s Jelly-derived mesenchymal stem cells on altered vascular functions in aged diabetic rat model

Fig. 4

MSCs-derived ECs counter vasoconstriction/vasodilatation imbalance in diabetic aged rats. a Aortic tissue level of nitric oxide (NO) in aged control (white column), aged diabetic (black column) and aged diabetic + ECs treated (grey column) groups. b Endothelial nitric oxide synthase (eNOS) gene expression in aged control (white column), aged diabetic (black column) and aged diabetic + ECs treated (grey column) groups. c Serum level of endothelin 1 (ET-1) in aged control (white column), aged diabetic (black column) and aged diabetic + ECs treated (grey column) groups. d Serum level of angiotensin II in aged control (white column), aged diabetic (black column) and aged diabetic + ECs treated (grey column) groups. (*Significant (p < 0.05), ns = non significant. Number of rats = 10/group)

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