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Table 5 Unadjusted and adjusted correlation of MALAT1 gene expression in SAT and VAT of the whole population study with energy homeostasis-related genes

From: Adipose tissue gene expression of long non-coding RNAs; MALAT1, TUG1 in obesity: is it associated with metabolic profile and lipid homeostasis-related genes expression?

CharacteristicslncRNA MALAT1 in SATlncRNA MALAT1 in VAT
 Whole PopulationWhole Population
Unadjusted Pearson coefficientAdjusted for age and HOMA-IR Pearson coefficientUnadjusted Pearson coefficientAdjusted for age and HOMA-IR Pearson coefficient
PPARγ0.329a0.2990.0700.086
PGC1α0.1530.2500.455b0.424b
SREBP0.640b0.589b0.2250.193
FAS0.573b0.513b0.2610.210
ACC0.411b0.401b0.1860.153
LncRNA TUG10.2990.346a− 0.380a− 0.324a
  1. SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue; MALAT1, metastasis-associated lung adenocarcinoma transcript 1; TUG1, taurine upregulated gene 1; PPARγ, peroxisome proliferator-activated receptor gamma; PGC1α, PPARγ coactivator-1 alpha; SREBP-1, sterol regulatory element-binding protein α; FAS, fatty acid synthase; ACC, acetyl-CoA carboxylase; HOMA-IR, homeostasis model assessment of insulin resistance
  2. a Correlation is significant at the 0.05 level (2-tailed)
  3. b Correlation is significant at the 0.01 level (2-tailed)