Adipose tissue gene expression of long non-coding RNAs; MALAT1, TUG1 in obesity: is it associated with metabolic profile and lipid homeostasis-related genes expression?

Table 2 Unadjusted and adjusted correlation of TUG1 gene expression in SAT and VAT of the whole population study with anthropometric and metabolic profiles

Characteristics	lncRNA TUG1 in SAT		lncRNA TUG1 in VAT
	Whole population		Whole population
	Unadjusted Pearson coefficient	Adjusted for age and HOMA-IR Pearson coefficient	Unadjusted Pearson coefficient	Adjusted for age and HOMA-IR Pearson coefficient
BMI, kg/m²	− 0.332^a	− 0.535^a	− 0.404^a	− 0.322
WC, cm	− 0.378^a	− 0.594^b	− 0.383^a	− 0.275
Hip, cm	− 0.425^b	− 0.732^b	− 0.433^b	− 0.340
WHR, -	0.014	0.116	0.026	0.097
FBG, mg/dL	− 0.164	− 0.138	− 0.016	0.068
Creatinine, mg/dL	− 0.465^b	− 0.577^b	0.015	0.295
eGFR, mL/min/1.73 m²	0.421^b	0.458^b	0.029	0.197
HDL-C, mg/dL	0.256	0.247	− 0.207	− 0.215
LDL-C, mg/dL	− 0.020	− 0.027	− 0.239	0.022
TC, mg/dL	− 0.096	− 0.112	− 0.239	0.045
TG, mg/dL	− 0.024	− 0.103	− 0.071	− 0.084
hs-CRP, mg/L	− 0.355^a	− 0.472^a	− 0.084	0.232
HOMA-IR, -	− 0.122	–	− 0.337^a	–
Insulin, µU/mL	− 0.103	–	− 0.344^a	–

BMI, body mass index; WC, waist circumference; WHR, waist-to-hip ratio; FBG, fasting blood glucose; HDL-high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides; hs-CRP, high-sensitivity C-reactive Protein; HOMA-IR, homeostasis model assessment of insulin resistance; eGFR, estimated glomerular filtration rate
^a Correlation is significant at the 0.05 level (2-tailed)
^b Correlation is significant at the 0.01 level (2-tailed)

ISSN: 1758-5996