Table 1 The anthropometric, clinical, and metabolic characterizations of the all participants
Characteristics | Normal-weight subjects (n = 19) | Obese subjects (n = 20) | Total difference p value |
|---|---|---|---|
Age, years | 38.84 ± 9.14 | 34.25 ± 5.81 | 0.073 |
BMI, kg/m2 | 23.49 (22.86–24.34) | 41.73 (36.35–46.77) | 0.000 |
WC, cm | 85 (83–87) | 114 (111.25–120) | 0.000 |
Hip, cm | 95 (90–97) | 128 (120–133.5) | 0.000 |
WHR, - | 0.89 ± 0.04 | 0.92 ± 0.05 | 0.068 |
SBP, mmHg | 117.05 ± 11.59 | 119.25 ± 14.26 | 0.602 |
DBP, mmHg | 80 (70–80) | 76.5 (62.5–87.5) | 0.971 |
FBG, mg/dL | 84.45 ± 7.36 | 86.42 ± 8.33 | 0.44 |
Urea nitrogen, mg/dL | 23.08 ± 7.78 | 25.62 ± 5.85 | 0.256 |
Creatinine, mg/dL | 0.57 ± 0.163 | 0.73 ± 0.10 | 0.001 |
Uric acid, mg/dL | 4.02 ± 0.72 | 5.43 ± 1.02 | 0.000 |
eGFR, mL/min/1.73 m2 | 138.31 ± 48.07 | 99.73 ± 17.57 | 0.002 |
HDL-C, mg/dL | 43.81 ± 6.34 | 45.10 ± 7.25 | 0.557 |
LDL-C, mg/dL | 88.43 ± 30.82 | 113.05 ± 20.67 | 0.006 |
TC, mg/dL | 146.51 ± 39.09 | 179.65 ± 26.58 | 0.004 |
TG, mg/dL | 93.1 (56.6–127.7) | 91.55 (59.87–123.25) | 0.786 |
VLDL-C, mg/dL | 21 (15–28) | 20 (17–28) | 0.679 |
LDL-C/HDL-C,- | 2.076 ± 0.79 | 2.5 ± 0.60 | 0.041 |
AST, U/L | 16.7 (12.5–21.4) | 21.1 (16.2–23.95) | 0.223 |
ALT, U/L | 12.9 (11–22.2) | 21.65 (15.35–30.2) | 0.406 |
ALP, U/L | 70.29 ± 26.73 | 72.88 ± 17.09 | 0.719 |
Albumin, g/dL | 3.7 (3.19–3.92) | 4.31 (4.2–4.43) | 0.000 |
TP, g/dL | 5.81 ± 0.83 | 6.81 ± 0.74 | 0.000 |
hs-CRP, mg/L | 1.8 (1.01–2.5) | 4.85 (2.9–10.29) | 0.000 |
HOMA-IR, - | 1.69 (0.93–2.24) | 3.85 (3.37–5.21) | 0.000 |
Insulin, µU/mL | 8.1 (4.63–9.93) | 19.45 (15.5–23.41) | 0.000 |