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Fig. 7 | Diabetology & Metabolic Syndrome

Fig. 7

From: Knockdown of lncRNA PVT1 alleviates high glucose-induced proliferation and fibrosis in human mesangial cells by miR-23b-3p/WT1 axis

Fig. 7

NF-κB signaling pathway was involved in PVT1-mediated regulation in HG-induced MCs via miR-23b-3p/WT1 axis. a, b The levels of p65 and p-p65 by western blot in MCs treated with HG or normal medium, or transfected with si-PVT1#1 + anti-miR-NC, si-PVT1#1 + anti-miR-23b-3p, si-PVT1#1 + pcDNA, or si-PVT1#1 + WT1 overexpression plasmid before HG treatment. pcDNA: nontarget negative plasmid, WT1: WT1 overexpression plasmid. *P < 0.05

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Diabetology & Metabolic Syndrome

ISSN: 1758-5996

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