Patient | 1 | 2 | ||
---|---|---|---|---|
Age (years old) | 15* | 30** | 1* | 12.2** |
Leptin (ng/mL)* | 1.0 | – | 1.0 | – |
Total cholesterol (mg/dL) | 292 | 175 | 131 | 145 |
HDL (mg/dL) | – | 25 | 26 | 18 |
HOMA-IR | NA | NA | 1.8 | 9.9 |
Glucose (fasting) (mg/dL) | 259 | 291 | 82 | 75 |
GlycohemoglobinA1c (%) | – | 6.4 | 5.1 | 5.7 |
Triglycerides (mg/dL) | 816 | 306 | 519 | 397 |
Abdominal ultrasound | – | Renal microlithiasis, hepatomegaly, hepatic steatosis, and nephromegaly | – | Hepatomegaly, hepatic steatosis, and nephromegaly |
Cardiovascular autonomic neuropathy testsa | – | Clinical/ Advanced | – | Absent |
Conventional echocardiography | – | increased left atrium, apical hypokinesia, preserved systolic function | – | Normal |
GLS by speckle-tracking echocardiography | – | − 17.9%b | – | − 19.3%b |