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Table 7 Correlations of urate and related variables with hemoglobin A1c in overall participants and participants with diabetes

From: Inverse associations between serum urate and glycemic status in a general population and in persons with diabetes mellitus

 

Univariate

Multivariate-1

Multivariate-2

Multivariate-3

Overall participants

 Urate

− 0.068 (p < 0.001)

− 0.074 (p < 0.001)

− 0.124 (p < 0.001)

− 0.092 (p < 0.001)

 Age

0.151 (p < 0.001)

0.205 (p < 0.001)

0.138 (p < 0.001)

 Therapy for diabetes

0.461 (p < 0.001)

0.460 (p < 0.001)

 Smoking

0.038 (p < 0.001)

0.029 (p = 0.001)

0.032 (p < 0.001)

 Alcohol drinking

0.054 (p < 0.001)

0.076 (p < 0.001)

0.065 (p < 0.001)

 Regular exercise

0.004 (p = 0.574)

0.022 (p = 0.008)

0.007 (p = 0.322)

 Body mass index

0.208 (p < 0.001)

0.222 (p < 0.001)

0.179 (p < 0.001)

 Systolic blood pressure

0.048 (p < 0.001)

0.037 (p < 0.001)

 log (triglycerides)

0.088 (p < 0.001)

0.090 (p < 0.001)

 HDL cholesterol

0.002 (p = 0.822)

0.015 (p = 0.092)

Diabetes

 Urate

− 0.188 (p < 0.001)

− 0.222 (p < 0.001)

− 0.254 (p < 0.001)

− 0.249 (p < 0.001)

 Age

− 0.170 (p < 0.001)

− 0.151 (p < 0.001)

− 0.140 (p < 0.001)

 Therapy for diabetes

− 0.104 (p = 0.003)

− 0.082 (p = 0.013)

 Smoking

0.031 (p = 0.359)

0.066 (p = 0.076)

0.039 (p = 0.231)

 Alcohol drinking

0.020 (p = 0.569)

0.051 (p = 0.121)

0.077 (p = 0.031)

 Regular exercise

0.009 (p = 0.781)

− 0.108 (p = 0.002)

0.030 (p = 0.352)

 Body mass index

0.114 (p = 0.002)

0.028 (p = 0.382)

0.057 (p = 0.127)

 Systolic blood pressure

0.091 (p = 0.009)

0.081 (p = 0.019)

 log (triglycerides)

0.309 (p < 0.001)

0.290 (p < 0.001)

 HDL cholesterol

0.127 (p = 0.001)

0.113 (p = 0.004)

  1. Shown are Pearson’s correlation coefficients in univariate analysis and standardized partial regression coefficients in multivariate analysis. Multivariate analysis was performed under three conditions (Multivariate 1–3) using different sets of explanatory variables
  2. The p value for each correlation coefficient is shown in parenthesis