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Table 6 Odds ratios for metabolic syndrome and its components in each quartile group vs. the 1st quartile group for urate in participants with diabetes

From: Inverse associations between serum urate and glycemic status in a general population and in persons with diabetes mellitus

 

1st quartile Urate: 0.8–4.7 mg/dl

2nd quartile Urate: 4.8–5.5 mg/dl

3rd quartile Urate: 5.6–6.4 mg/dl

4th quartile Urate: 6.5–12.9 mg/dl

Metabolic syndrome

 Crude

1.00

1.29 (0.87–1.93)

1.13 (0.77–1.66)

1.48 (0.99–2.23)

 Adjusted

1.00

1.17 (0.68–2.00)

0.82 (0.49–1.37)

0.71 (0.40–1.25)

High WHtR

 Crude

1.00

1.10 (0.73–1.66)

1.16 (0.78–1.74)

1.35 (0.88–2.07)

 Adjusted

1.00

1.08 (0.71–1.64)

1.12 (0.75–1.70)

1.27 (0.82–1.97)

Hypertension

 Crude

1.00

1.36 (0.91–2.02)

1.31 (0.89–1.93)

1.97 (1.30–2.98)**

 Adjusted

1.00

1.25 (0.80–1.95)

1.13 (0.74–1.74)

1.55 (0.98–2.45)

Hyper-triglyceridemia

 Crude

1.00

1.34 (0.88–2.05)

1.39 (0.92–2.10)

1.76 (1.15–2.68)**

 Adjusted

1.00

1.25 (0.81–1.92)

1.22 (0.80–1.89)

1.45 (0.92–2.29)

Hypo-HDL cholesterolemia

 Crude

1.00

1.75 (0.98–3.12)

1.39 (0.78–2.50)

1.87 (1.04–3.34)**

 Adjusted

1.00

1.68 (0.92–3.06)

1.55 (0.83–2.87)

1.86 (0.97–3.57)

  1. Odds ratios with their 95% confidence intervals for each variable are shown. The range of uric acid levels in each quartile group is shown in the table. In multivariate analysis, adjusted odds ratios were estimated using age and histories of smoking, alcohol drinking and regular exercise as other explanatory variables. BMI was also adjusted in analysis for variables except for high WHtR. In addition, a history of medication therapy for hypertension or dyslipidemia was used as an explanatory variable in multivariate analysis for hypertension, hyper-triglyceridemia and hypo-HDL cholesterolemia
  2. Asterisks denote significant differences from the reference level of 1.00 (** p < 0.01)