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Table 3 Odds ratios for metabolic syndrome and its components in each quartile group vs. the 1st quartile group for urate in overall participants

From: Inverse associations between serum urate and glycemic status in a general population and in persons with diabetes mellitus

 

1st quartile

Urate: 0.3–5.1 mg/dl

2nd quartile

Urate: 5.2–5.9 mg/dl

3rd quartile

Urate: 6.0–6.7 mg/dl

4th quartile

Urate: 6.8–12.9 mg/dl

Metabolic syndrome

 Crude

1.00

1.06 (0.89–1.27)

1.30 (1.10–1.55)**

2.10 (1.79–2.45)**

 Adjusted

1.00

1.16 (0.97–1.39)

1.51 (1.26–1.80)**

2.37 (2.01–2.79)**

High WHtR

 Crude

1.00

1.29 (1.16–1.43)**

1.75 (1.58–1.95)**

2.80 (2.52–3.10)**

 Adjusted

1.00

1.42 (1.27–1.58)**

2.03 (1.82–2.27)**

3.36 (3.01–3.75)**

Hypertension

 Crude

1.00

1.07 (0.95–1.20)

1.37 (1.22–1.53)**

2.05 (1.83–2.28)**

 Adjusted

1.00

1.03 (0.90–1.17)

1.26 (1.10–1.43)**

1.67 (1.47–1.90)**

Hyper-triglyceridemia

 Crude

1.00

1.21 (1.07–1.37)**

1.81 (1.61–2.04)**

3.12 (2.79–3.50)**

 Adjusted

1.00

1.10 (0.97–1.25)

1.54 (1.36–1.75)**

2.45 (2.17–2.77)**

Hypo-HDL cholesterolemia

 Crude

1.00

1.41 (1.17–1.70)**

1.59 (1.32–1.92)**

1.95 (1.63–2.33)**

 Adjusted

1.00

1.40 (1.15–1.70)**

1.55 (1.27–1.89)**

1.72 (1.41–2.09)**

Diabetes

 Crude

1.00

0.75 (0,62–0.90)**

0.58 (0.48–0.71)**

0.48 (0.39–0.60)**

 Adjusted

1.00

0.71 (0.59–0.87)**

0.51 (0.41–0.63)**

0.35 (0.28–0.44)**

  1. Odds ratios with their 95% confidence intervals for each variable are shown. The range of urate levels in each quartile group is shown in the table. In multivariate analysis, adjusted odds ratios were estimated using age and histories of smoking, alcohol drinking and regular exercise as other explanatory variables. BMI was also adjusted in analysis of variables except for high WHtR. In addition, a history of medication therapy for hypertension, dyslipidemia or diabetes was used as an explanatory variable in multivariate analysis for hypertension, hyper-triglyceridemia, hypo-HDL cholesterolemia and diabetes
  2. Asterisks denote significant differences from the reference level of 1.00 (** p < 0.01)