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Table 2 Levels of remodeling markers at baseline and after 12-months of intervention in the randomized groups

From: Effects of exercise training on markers of adipose tissue remodeling in patients with coronary artery disease and type 2 diabetes mellitus: sub study of the randomized controlled EXCADI trial

 ControlExercise∆pRelative ∆p
Baseline12-monthsp1Baseline12-monthsp2
AT-MMP91.98 (0.89, 3.26)1.61 (0.97, 3.50)0.5861.57 (0.82, 3.05)1.18 (0.89, 1.91)0.1840.6500.767
AT-TIMP11.02 (0.79, 1.15)1.08 (0.79, 1.43)0.4760.96 (0.75, 1.30)0.99 (0.80, 1.45)0.4950.9080.929
AT-EMMPPRIN0.99 (0.73, 1.28)0.82 (0.61, 1.25)0.0210.86 (0.73, 1.06)0.95 (0.66, 1.26)0.1460.008*0.018*
AT-Galectin-31.03 (0.69, 1.38)0.96 (0.64, 1.30)0.0151.05 (0.83, 1.31)1.00 (0.70, 1.24)0.1790.3660.366
L-MMP90.79 (0.57, 1.30)0.72 (0.47, 1.47)0.8370.86 (0.60, 1.58)0.77 (0.61, 1.27)0.1580.4800.544
L-TIMP10.98 (0.68, 1.61)1.04 (0.67, 1.64)0.6541.09 (0.88, 1.71)0.96 (0.70, 1.63)0.3130.8220.434
L-EMMPRIN0.66 (0.36, 1.00)0.61 (0.27, 1.24)0.5990.63 (0.45, 1.03)0.60 (0.35, 0.82)0.0350.2710.388
L-Galectin-30.94 (0.68, 1.35)0.94 (0.55, 1.41)0.2731.04 (0.71, 1.35)0.80 (0.61, 1.29)0.0300.2840.411
sMMP9317 (198, 416)288 (189, 431)0.956308 (215, 427)335 (257, 490)0.0540.1520.052
sTIMP1158 (140, 175)160 (143, 184)0.328158 (140, 184)168 (149, 191)0.0010.0660.082
sEMMPRIN3748 (3432, 4118)3707 (3515, 4100)0.9083848 (3391, 4404)3983 (3452, 4521)0.0070.033*0.036*
sGalectin-310.6 (8.1, 12.7)10.0 (8.3, 11.6)0.80610.3 (8.3, 11.7)10.2 (8.6, 12.3)0.0740.1380.246
  1. Values are median (25, 75 percentiles)
  2. AT refers to gene expression in adipose tissue, L refers to gene expression in circulating leukocytes, s indicate serum
  3. p1-values refer to changes within the control group from baseline to 12 months (Wilcoxon Signed Rank test)
  4. p2-values refer to changes within the exercise group from baseline to 12 months (Wilcoxon Signed Rank test)
  5. p-values in italics indicate statistically significant values
  6. Delta p (Δp) refers to difference in change between the groups during intervention (Mann–Whitney test)
  7. Relative delta p (Δp) refers to difference in change between the groups during intervention as related to baseline levels
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