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Table 1 Baseline characteristics of the total study population (n = 137) and according to the randomized groups

From: Effects of exercise training on markers of adipose tissue remodeling in patients with coronary artery disease and type 2 diabetes mellitus: sub study of the randomized controlled EXCADI trial

 

All (137)

Exercise (52)

Control (62)

Age

64 (58, 69)

65 (58, 70)

64 (60, 68)

Sex (m/f)

115/22

45/7

51/11

Previous AMI, n (%)

62 (45)

20 (39)

31 (49)

Advanced vascular disease, n (%)a

79 (57)

28 (54)

41 (66)

CHF, n (%)

11 (8)

2 (4)

5 (8)

PAD, n (%)

13 (9, 5)

3 (6)

6 (10)

Years with DM

9.0 (5, 15)

11.0 (5.0, 15.0)

9.0 (5.5, 13.5)

Hypertension, n (%)

100 (73)

39 (75)

48 (76)

Current smokers, n (%)

23 (16.8)

9 (17)

9 (14)

SBP (mmHg)

138 (127, 150)

136 (129, 150)

140 (126, 150)

DBP (mmHg)

79 (71, 86)

76 (71, 82)

81 (71, 87)

Weight (kg)

86.5 (77.1, 97.0)

87.0 (78.5, 99.0)

85.0 (77.5, 96.0)

HbA1c (%)

7.4 (6.8, 8.3)

7.4 (6.8, 8.4)

7.4 (6.8, 8.0)

Insulin (pmol/L)

57 (33, 101)

54 (31, 95)

63 (32, 104)

C-peptide (pmol/L)

965 (713, 1290)

956 (637, 1165)

1042 (743, 1453)

Total cholesterol (mmol/L)

3.9 (3.4, 4.6)

3.8 (3.4, 4.3)

4.0 (3.3, 4.8)

Triglycerides (mmol/L)

1.42 (1.06, 1.91)

1.44 (1.09, 1.86)

1.36 (0.99, 1.88)

LDL (mmol/L)

2.0 (1.6, 2.6)

1.8 (1.5, 2.5)

2.2 (1.6, 2.9)

HOMA2-IR

1.3 (0.7, 2.1)

1.1 (0.7, 1.9)

1.3 (0.7, 2.2)

BMI (kg/m2)

28.7 (25.7, 31.6)

29.4 (25.5, 31.8)

28.1 (25.6, 31.6)

Medication, n (%)

 ACE-inhibitors

43 (31.6)

14 (27)

21 (34)

 A2-blockers

55 (40.1)

20 (38)

25 (40)

 Statins

128 (93.4)

49 (94)

59 (95)

 Metformin

101 (73.7)

40 (77)

46 (74)

 Sulfonylureas

48 (35.0)

23 (44)

18 (29)

 Gliptin

17 (12.4)

6 (12)

11 (18)

 Insulin

26 (19.1)

12 (17.4)

14 (20.9)

 Anti-platelet drugs

129 (94)

47 (90)

61 (98)*

  1. Values are given as number (proportions), or median (25, 75 percentile)
  2. AMI acute myocardial infarction, SBP systolic blood pressure, DBP diastolic blood pressure, DM diabetes mellitus, LDL low-density lipoprotein, CHF congestive heart failure, PAD peripheral artery disease, HOMA2-IR homeostatic model assessment indexes-insulin resistance, BMI body mass index, ACE angiotensin converting enzyme, A2 angiotensin II
  3. p-values refer to differences between the exercise and control group
  4. * p = 0.054
  5. aAdvanced vascular disease is defined as those with previous MI and/or diabetic microvascular complications in addition to CAD