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Table 1 Baseline characteristics of the total study population (n = 137) and according to the randomized groups

From: Effects of exercise training on markers of adipose tissue remodeling in patients with coronary artery disease and type 2 diabetes mellitus: sub study of the randomized controlled EXCADI trial

 All (137)Exercise (52)Control (62)
Age64 (58, 69)65 (58, 70)64 (60, 68)
Sex (m/f)115/2245/751/11
Previous AMI, n (%)62 (45)20 (39)31 (49)
Advanced vascular disease, n (%)a79 (57)28 (54)41 (66)
CHF, n (%)11 (8)2 (4)5 (8)
PAD, n (%)13 (9, 5)3 (6)6 (10)
Years with DM9.0 (5, 15)11.0 (5.0, 15.0)9.0 (5.5, 13.5)
Hypertension, n (%)100 (73)39 (75)48 (76)
Current smokers, n (%)23 (16.8)9 (17)9 (14)
SBP (mmHg)138 (127, 150)136 (129, 150)140 (126, 150)
DBP (mmHg)79 (71, 86)76 (71, 82)81 (71, 87)
Weight (kg)86.5 (77.1, 97.0)87.0 (78.5, 99.0)85.0 (77.5, 96.0)
HbA1c (%)7.4 (6.8, 8.3)7.4 (6.8, 8.4)7.4 (6.8, 8.0)
Insulin (pmol/L)57 (33, 101)54 (31, 95)63 (32, 104)
C-peptide (pmol/L)965 (713, 1290)956 (637, 1165)1042 (743, 1453)
Total cholesterol (mmol/L)3.9 (3.4, 4.6)3.8 (3.4, 4.3)4.0 (3.3, 4.8)
Triglycerides (mmol/L)1.42 (1.06, 1.91)1.44 (1.09, 1.86)1.36 (0.99, 1.88)
LDL (mmol/L)2.0 (1.6, 2.6)1.8 (1.5, 2.5)2.2 (1.6, 2.9)
HOMA2-IR1.3 (0.7, 2.1)1.1 (0.7, 1.9)1.3 (0.7, 2.2)
BMI (kg/m2)28.7 (25.7, 31.6)29.4 (25.5, 31.8)28.1 (25.6, 31.6)
Medication, n (%)
 ACE-inhibitors43 (31.6)14 (27)21 (34)
 A2-blockers55 (40.1)20 (38)25 (40)
 Statins128 (93.4)49 (94)59 (95)
 Metformin101 (73.7)40 (77)46 (74)
 Sulfonylureas48 (35.0)23 (44)18 (29)
 Gliptin17 (12.4)6 (12)11 (18)
 Insulin26 (19.1)12 (17.4)14 (20.9)
 Anti-platelet drugs129 (94)47 (90)61 (98)*
  1. Values are given as number (proportions), or median (25, 75 percentile)
  2. AMI acute myocardial infarction, SBP systolic blood pressure, DBP diastolic blood pressure, DM diabetes mellitus, LDL low-density lipoprotein, CHF congestive heart failure, PAD peripheral artery disease, HOMA2-IR homeostatic model assessment indexes-insulin resistance, BMI body mass index, ACE angiotensin converting enzyme, A2 angiotensin II
  3. p-values refer to differences between the exercise and control group
  4. * p = 0.054
  5. aAdvanced vascular disease is defined as those with previous MI and/or diabetic microvascular complications in addition to CAD
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