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Table 3 The effect of genistein on lipid levels of women (mean ± SD)

From: The effect of genistein on lipid levels and LDLR, LXRα and ABCG1 expression in postmenopausal women with hyperlipidemia

Lipids

 

Baseline

6 months

ap

bp

Cholesterol (mmol/L)

PG

6.7 ± 1.1

6.6 ± 1.1

0.2108

0.199

EG

6.7 ± 1.1

6.1 ± 1.1

0.0283

 

Triglyceride (mmol/L)

PG

3.0 ± 1.1

3.0 ± 1.2

0.3382

0.001

EG

3.0 ± 0.9

2.4 ± 1.1

0.0006

 

HDL-C (mmol/L)

PG

1.1 ± 0.2

1.0 ± 0.3

0.2391

0.438

EG

1.1 ± 0.1

1.2 ± 0.1

0.0131

 

LDL-C (mmol/L)

PG

5.3 ± 1.1

5.3 ± 1.4

0.3912

0.000

EG

5.2 ± 1.0

3.8 ± 0.6

0.0015

 

HDL/LDL (mmol/L)

PG

0.2 ± 0.1

0.2 ± 0.1

0.3732

0.003

EG

0.2 ± 0.1

0.3 ± 0.1

0.0013

 

Apo-A1 (g/L)

PG

1.19 ± 0.04

1.18 ± 0.02

0.2117

0.438

EG

1.19 ± 0.03

1.19 ± 0.02

0.4201

 

Apo-B (g/L)

PG

1.01 ± 0.04

1.00 ± 0.03

0.2301

0.044

EG

1.02 ± 0.04

0.68 ± 0.06

0.0469

 
  1. PG Placebo group, EG experiment group
  2. Experimental conditions and treatment procedures are given in Materials and methods. Graph depicts (mean ± SD). ap value denotes the comparison of mean changes from respective baseline between the experiment group and placebo group by two-sample t test. bp value indicates the comparison of mean change from respective baseline between the experiment and placebo group were evaluated by Tukey test. PG Placebo group, EG experiment group