Table 3 Binary logistic regression analyses of variables contributing to DPN in patients with T2DM
Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
B | OR (95% CI) | P-value | B | OR (95% CI) | P-value | |
Sex | − 0.330 | 0.719 (0.536–0.965) | 0.028 | |||
Age | 0.071 | 1.074 (1.057–1.091) | 0.000 | 0.043 | 1.044 (1.010–1.079) | 0.011 |
BMI | − 0.059 | 0.943 (0.902–0.984) | 0.008 | |||
Diabetes duration | 0.071 | 1.073 (1.051–1.096) | 0.000 | |||
PP | 0.015 | 1.016 (1.008–1.023) | 0.000 | |||
MAP | 0.000 | 1.000 (0.988–1.011) | 0.953 | |||
FBG | 0.031 | 1.032 (1.005–1.059) | 0.019 | |||
HbA1c | 0.111 | 1.117 (1.057–1.181) | 0.000 | |||
TC | − 0.147 | 0.863 (0.765–0.974) | 0.017 | |||
TG | − 0.161 | 0.851 (0.765–0.947) | 0.003 | |||
HDL-C | − 0.028 | 0.972 (0.638–1.482) | 0.895 | |||
LDL-C | − 0.046 | 0.955 (0.821–1.110) | 0.547 | |||
ApoA | − 0.984 | 0.374 (0.220–0.634) | 0.000 | |||
ApoB | 0.038 | 1.039 (0.626–1.725) | 0.882 | |||
ApoB/ApoA | 0.719 | 2.052 (1.230–3.423) | 0.006 | 3.871 | 48.012 (1.478–1560) | 0.029 |
TBIL | − 0.119 | 0.888 (0.851–0.927) | 0.000 | − 0.113 | 0.893 (0.828–0.964) | 0.004 |
ALT | − 0.056 | 0.945 (0.926–0.964) | 0.000 | |||
AST | − 0.045 | 0.956 (0.931–0.981) | 0.001 | |||
Neutrophil count | 0.153 | 1.166 (1.099–1.237) | 0.000 | |||
Lymphocyte count | − 0.674 | 0.510 (0.385–0.675) | 0.000 | |||
NLR | 0.117 | 1.124 (1.073–1.177) | 0.000 | |||
WBC count | 0.115 | 1.122 (1.063–1.185) | 0.000 | |||
PT | 0.360 | 1.434 (1.228–1.673) | 0.000 | |||
APTT | 0.040 | 1.041 (1.013–1.070) | 0.004 | |||
INR | 4.457 | 86.264(11.060–672.807) | 0.000 | |||
Fibrinogen | 0.431 | 1.540 (1.346–1.761) | 0.000 | |||
eGFR | − 0.022 | 0.978 (0.973–0.983) | 0.000 | |||
Crea | 0.006 | 1.006 (1.003–1.009) | 0.000 | |||
Hypertension | 0.547 | 1.728 (1.277–2.337) | 0.000 | |||
CHD | 0.923 | 2.518 (1.660–3.819) | 0.000 | |||
Stroke | 0.766 | 2.150 (1.559–2.966) | 0.000 | |||
DFU | 1.729 | 5.636 (3.689–8.611) | 0.000 | 1.072 | 2.922 (1.435–5.950) | 0.003 |
PAD | 1.567 | 4.791 (3.279–6.999) | 0.000 | |||
DN | 0.781 | 2.184 (1.624–2.936) | 0.000 | |||
DR | 0.849 | 2.337 (1.607–3.398) | 0.000 | |||