Diabetology & Metabolic Syndrome

Table 2 Linear correlation and multiple regression analysis of variables associated with serum TBIL in the entire population studied

From: Physiological serum total bilirubin concentrations were inversely associated with diabetic peripheral neuropathy in Chinese patients with type 2 diabetes: a cross-sectional study

Variable	Simple				Multiple
Variable	r	P-value	Adjusted r	Adjusted P-value	β	Standardized β	P-value
Age	− 0.071	0.010
Sex	− 0.095	0.000			− 1.012	− 0.128	0.004
BMI	0.047	0.091
Diabetic duration	− 0.132	0.000
SBP	− 0.045	0.101	− 0.084	0.067
DBP	0.070	0.010	0.041	0.370
PP	− 0.084	0.002	− 0.131	0.004
MAP	0.021	0.435	− 0.017	0.712
FBG	0.019	0.489	− 0.049	0.281
HbA1c	− 0.011	0.698	− 0.069	0.129
TC	0.095	0.001	0.041	0.365
TG	− 0.066	0.016	− 0.095	0.038
HDL-C	0.172	0.000	0.175	0.000	1.557	0.140	0.002
LDL-C	0.075	0.007	0.014	0.753
ApoA	0.177	0.000	0.182	0.000
ApoB	0.039	0.161	− 0.015	0.738
ApoB/ApoA	− 0.068	0.014	− 0.107	0.019
DBIL	0.779	0.000	0.770	0.000
IBIL	0.951	0.000	0.947	0.000
ALT	0.163	0.000	0.125	0.006	0.046	0.101	0.019
AST	0.123	0.000	0.118	0.009
Neutrophil count	− 0.074	0.008	− 0.127	0.005
Lymphocyte count	− 0.045	0.107	0.013	0.785
NLR	− 0.019	0.506	− 0.120	0.009
WBC count	− 0.102	0.000	− 0.122	0.008
PT	0.046	0.237	0.032	0.484	0.823	0.248	0.001
APTT	0.014	0.716	0.038	0.408
INR	0.012	0.766	− 0.024	0.599	− 7.203	− 0.152	0.037
Fibrinogen	− 0.165	0.000	− 0.206	0.000	− 0.357	− 0.119	0.010
ACR	− 0.227	0.000	− 0.167	0.000	− 1.141	− 0.216	0.000
eGFR	0.166	0.000	0.077	0.093
Crea	− 0.112	0.000	− 0.075	0.099
VPT	− 0.165	0.000	− 0.144	0.002	− 0.032	− 0.089	0.047
ABI	0.038	0.166	0.041	0.368
Hypertension	− 0.108	0.000	− 0.098	0.000
CHD	0.023	0.393	0.054	0.052
Stroke	− 0.042	0.126	− 0.008	0.768
DFU	− 0.126	0.000	− 0.117	0.000
PAD	− 0.058	0.033	− 0.025	0.364
DPN	− 0.149	0.000	− 0.139	0.000
DN	− 0.144	0.000	− 0.130	0.000
DR	− 0.145	0.000	− 0.119	0.000

In multiple linear stepwise regression analysis, values included for analysis in T2DM patients were sex, age, BMI, diabetic duration, blood pressure (SBP, DBP, PP, and MAP), glycemic control (FBG and HbA1C), Lipid profiles (TG, TC, HDL-C, LDL-C, ApoB, ApoB, and ApoB/ApoA), liver function (ALT and AST), inflammatory markers (neutrophil, lymphocyte, NLR, and WBC counts), coagulation function (PT, APTT, INR, and fibrinogen), renal function (urinary ACR, eGFR, and Crea), VPT values, and ABI

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ISSN: 1758-5996

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