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Table 3 Comparison between patients wit Systemic Lupus Erythematosus with abnormal TyG index and normal TyG index

From: Fasting triglycerides and glucose index: a useful screening test for assessing insulin resistance in patients diagnosed with rheumatoid arthritis and systemic lupus erythematosus

Variables

SLE

Abnormal TyG

Index

n = 28

SLE

Normal TyG

index

n = 29

p

Age (yrs) mean ± SD

47.1 ± 11

46.5 ± 8.6

0.8

Disease duration (years), mean ± SD

13.0 ± 7.7

11.2 ± 7.7

0.2

Smoking, n (%)

4 (14.3)

5 (17.2)

1.0

Sedentary lifestyle, n (%)

13 (46.4)

20 (69)

0.08

Hypertension, n (%)

10 (35.7)

6 (20.7)

0.2

Duration of hypertension (years), mean ± SD

3.0 ± 6.4

1.1 ± 4.8

0.06

Menopause, n (%)

15 (53.6)

15 (51.7)

0.8

Body mass index (kg/m2), mean ± SD

30.0 ± 5.1

28.1 ± 5.1

0.1

Waist (cm), mean ± SD

96.9 ± 12.8

88.7 ± 13.8

0.02

Total-cholesterol (mg/dL), mean ± SD

214.7 ± 42.9

181.0 ± 31.6

0.001

 Total-cholesterol (mmol/L), mean ± SD

5.5 ± 1.1

4.6 ± 0.8

0.001

HDL-cholesterol (mg/dL), mean ± SD

49.8 ± 14.2

54.2 ± 14.9

0.2

 HDL-cholesterol (mmol/L), mean ± SD

1.2 ± 0.3

1.4 ± 0.3

0.2

LDL-cholesterol (mg/dL), mean ± SD

123.9 ± 35.1

108.0 ± 24.6

0.05

 LDL-cholesterol (mmol/L), mean ± SD

3.2 ± 0.9

2.7 ± 0.6

0.05

Uric Acid(mg/dL), mean ± SD

5.0 ± 1.2

4.3 ± 0.9

0.01

 Uric Acid(mmol/L), mean ± SD

2.9 ± 0.7

2.5 ± 0.5

0.01

Fat mass% (DXA results), mean ± SD

50.2 ± 4.5

46.7 ± 4.4

0.007

Treatments

 Corticosteroid, n (%)

28 (100)

26 (89.6)

0.2

 Chloroquine, n (%)

13 (46.8)

13 (44.8)

1.0

 Methotrexate, n (%)

4 (14.3)

5 (17.2)

1.0

 Leflunomide, n (%)

2 (7.1)

3 (10.3)

1.0

 Biologics, n (%)

7 (25)

6 (20.7)

0.6

  1. Italic values indicate significance of p value (p < 0.05)
  2. An abnormal TyG index (TyG index > 4.68) suggests insulin resistance; HDL-cholesterol high density lipoprotein-cholesterol, LDL-cholesterol low density lipoprotein-cholesterol, DXA dual-energy X-ray absortiometry; TyG values are expressed in mean and standard deviation SD; comparisons between proportions were calculated by Χ2 test or Fisher´s exact test; comparisons between means by unpaired Student-t test; biologics included in the analysis: adalimumab, rituximab, infliximab