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Table 1 Definitions of various protocols for screening of gestational diabetes mellitus

From: Cost effectiveness of different screening strategies for gestational diabetes mellitus screening: study protocol of a randomized community non-inferiority trial

Protocol

First trimester

Second trimester

Diagnostic criteria for GDM

Method for GDM screening

Diagnostic threshold of test

Diagnostic criteria

A

92 mg/dL < FPG > 126 mg/dL

One step with 2-h 75 g OGTT

Fasting ≥ 92 mg/dL

1 h ≥ 180 mg/dL

2 h ≥ 153 mg/dL

GDM is defined as any of the given plasma glucose values are met or exceeded

B

100 mg/dL < FPG > 126 mg/dL

One step with 2-h 75 g OGTT

Fasting ≥ 92 mg/dL

1 h ≥ 180 mg/dL

2 h ≥ 153 mg/dL

GDM is defined as two or more of the given plasma glucose values are met or exceeded

C

100 mg/dL < FPG > 126 mg/dL

One step with 2-h 75 g OGTT

Fasting ≥ 92 mg/dL

1 h ≥ 180 mg/dL

2 h ≥ 153 mg/dL

GDM is defined as any of the given plasma glucose values are met or exceeded

D

92 mg/dL < FPG > 126 mg/dL

Two steps with 50 g GCT—1 h following

3-h 100 g OGTT

50 g GCT:

GDM is defined as if two or more of the given plasma glucose values in 100 g OGTT are met or exceeded

  BS-1 h: ≥ 140 mg

100 g OGTT:

  Fasting ≥ 95 mg/dL

  1 h ≥ 180 mg/dL

  2 h ≥ 155 mg/dL

  3 h ≥ 140 mg/dL

E

100 mg/dL < FPG > 126 mg/dL

Two steps with 50 g GCT—1 h following

3-h 100 g OGTT

50 g GCT:

GDM is defined as if two or more of the given plasma glucose values in 100 g OGTT are met or exceeded

  BS-1 h: ≥ 140 mg

100 g OGTT:

  Fasting ≥ 95 mg/dL

  1 h ≥ 180 mg/dL

  2 h ≥ 155 mg/dL

  3 h ≥ 140 mg/dL

  1. In the first trimester overt diabetes is defined as FPG ≥ 126 mg/dL
  2. FPG fasting plasma glucose, GCT glucose challenge test, OGTT oral glucose tolerance test