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Table 1 Definitions of various protocols for screening of gestational diabetes mellitus

From: Cost effectiveness of different screening strategies for gestational diabetes mellitus screening: study protocol of a randomized community non-inferiority trial

ProtocolFirst trimesterSecond trimester
Diagnostic criteria for GDMMethod for GDM screeningDiagnostic threshold of testDiagnostic criteria
A92 mg/dL < FPG > 126 mg/dLOne step with 2-h 75 g OGTTFasting ≥ 92 mg/dL
1 h ≥ 180 mg/dL
2 h ≥ 153 mg/dL
GDM is defined as any of the given plasma glucose values are met or exceeded
B100 mg/dL < FPG > 126 mg/dLOne step with 2-h 75 g OGTTFasting ≥ 92 mg/dL
1 h ≥ 180 mg/dL
2 h ≥ 153 mg/dL
GDM is defined as two or more of the given plasma glucose values are met or exceeded
C100 mg/dL < FPG > 126 mg/dLOne step with 2-h 75 g OGTTFasting ≥ 92 mg/dL
1 h ≥ 180 mg/dL
2 h ≥ 153 mg/dL
GDM is defined as any of the given plasma glucose values are met or exceeded
D92 mg/dL < FPG > 126 mg/dLTwo steps with 50 g GCT—1 h following
3-h 100 g OGTT
50 g GCT:GDM is defined as if two or more of the given plasma glucose values in 100 g OGTT are met or exceeded
  BS-1 h: ≥ 140 mg
100 g OGTT:
  Fasting ≥ 95 mg/dL
  1 h ≥ 180 mg/dL
  2 h ≥ 155 mg/dL
  3 h ≥ 140 mg/dL
E100 mg/dL < FPG > 126 mg/dLTwo steps with 50 g GCT—1 h following
3-h 100 g OGTT
50 g GCT:GDM is defined as if two or more of the given plasma glucose values in 100 g OGTT are met or exceeded
  BS-1 h: ≥ 140 mg
100 g OGTT:
  Fasting ≥ 95 mg/dL
  1 h ≥ 180 mg/dL
  2 h ≥ 155 mg/dL
  3 h ≥ 140 mg/dL
  1. In the first trimester overt diabetes is defined as FPG ≥ 126 mg/dL
  2. FPG fasting plasma glucose, GCT glucose challenge test, OGTT oral glucose tolerance test