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Table 3 GMDR analysis for the best interaction combination models

From: Interaction between ELMO1 gene polymorphisms and environment factors on susceptibility to diabetic nephropathy in Chinese Han population

Locus no.Best combinationCross-validation consistencyTesting balanced accuracyp-values*
Gene–hypertension interactionsa
 21, hypertension8/100.5980.6241
 31, 3, hypertension6/100.5620.377
 41, 2, 3, hypertension5/100.5450.857
 51, 2, 3, 4, hypertension7/100.5210.377
Gene–alcohol drinking interactionsb
 21, alcohol drinking10/100.6210.0107
 31, 3, alcohol drinking8/100.5990.1719
 41, 2, 4, alcohol drinking7/100.5580.3770
 51, 2, 3, 4, alcohol drinking8/100.4760.5316
  1. SNPs named with 1–4 were rs741301, rs1345365, rs10255208 and rs7782979 respectively
  2. aAdjusted for age, gender, BMI, smoking and alcohol drinking
  3. bAdjusted for age, gender, BMI, hypertension and smoking