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Table 2 Metabolic characters of rats after 6-month treatment

From: Long-term treatment with metformin in the prevention of fatty liver in Zucker diabetic fatty rats

 Zucker lean, n = 6ZDF + Met, n = 7ZDF + V, n = 7
Body weight (g)390 ± 12491 ± 29a485 ± 49b
2-h OGTT blood glucose (mmol/L)7.9 ± 1.711.4 ± 2.3ac14.7 ± 2.3b
Serum total cholesterol (mmol/L)1.07 ± 0.074.9 ± 1.0a5.0 ± 0.6b
Serum triglyceride (mmol/L)0.32 ± 0.028.9 ± 3.3a8.7 ± 1.9b
Serum total protein (g/L)70.0 ± 1.770.6 ± 1.773.0 ± 2.3
Serum albumin (g/L)20.7 ± 0.616.1 ± 2.0a15.7 ± 1.4b
ALT (U/L)79.3 ± 11.4139.9 ± 25.9a155.7 ± 79.2b
AST (U/L)86.7 ± 6.1120.6 ± 22.8a156.3 ± 61.0b
  1. Data are mean ± SD
  2. OGTT oral glucose tolerance test, ALT alanine aminotransferase, AST aspartate transaminase
  3. a,bp < 0.05 versus Zucker lean, c p < 0.05 versus V