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Table 1 Body weight, adipose tissue weight and metabolic profile of C57BL/6J mice among different groups (mean ± SEM)

From: Effects of metformin on metabolism of white and brown adipose tissue in obese C57BL/6J mice

 

ND

HFD

MET

WAT mass (%)

2.16 ± 0.38**

4.74 ± 0.57

4.56 ± 0.34

BAT mass (%)

0.26 ± 0.04*

0.14 ± 0.02

0.20 ± 0.03

TC (mg/dl)

38.95 ± 0.82***

76.20 ± 3.04

72.71 ± 1.88

TG (mg/dl)

61.45 ± 1.70**

75.88 ± 3.15

62.38 ± 1.39**

Leptin (pg/ml)

687.56 ± 50.46***

1144.19 ± 70.59

707.91 ± 48.81***

Adiponectin (ng/ml)

4.98 ± 0.13***

3.34 ± 0.26

4.09 ± 0.15*

Resistin (pg/ml)

793.91 ± 84.14

811.32 ± 75.58

667.40 ± 47.91

  1. ND normal diet, HFD high fat diet, MET metformin, WAT white adipose tissue, BAT brown adipose tissue, TC total cholesterol, TG triglyceride. *Compared with HFD group.*p < 0.05, **p < 0.01, ***p < 0.001