Treatment patterns of drug-naive patients with type 2 diabetes mellitus: a retrospective cohort study using a Japanese hospital database

Table 1 Baseline demographics and clinical characteristics of drug-naive patients with T2DM treated with first-line AD therapy in the outpatient setting

Characteristics	Drug-naive patients (N = 224,761)
Gender (men)	137,391 (61.2%)
Age (years), mean (SD)	65.6 (13.0)
BMI^a (kg/m²), mean (SD)	24.64 (4.6)
HbA1c level (%)^a, mean (SD)	7.99 (1.9)
Normal: < 6.0%	746 (0.3%)
Patients with HbA1c level between 6.0% and < 7.0%	4575 (2.0%)
Patients with HbA1c level between 7.0% and < 8.0%	5162 (2.3%)
Patients with HbA1c level ≥ 8.0%	5946 (2.7%)
Comorbidities^a
Coronary heart disease and stroke	69,371 (30.9%)
Liver disease	49,199 (21.9%)
Diabetic nephropathy	25,065 (11.2%)
Diabetic retinopathy	24,553 (10.9%)
Diabetic neuropathy	21,147 (9.4%)
Dyslipidemia	129,103 (57.44%)
Hypertension	139, 665 (62.14%)
Renal disease	20,118 (9.0%)
Therapy use
Antihypertensive drugs	115,576 (51.42%)
Antidyslipidemic drugs	93,863 (41.76%)
Antithrombotic drugs	62,430 (27.78%)
Total visits^a, mean (SD)	3.8 (5.8)

AD antidiabetes, BMI body mass index, HbA1c glycated hemoglobin, SD standard deviation, T2DM type 2 diabetes mellitus
^aAssessed within 180 days before the index date. Values are presented as n (%) unless otherwise stated. % is defined as n/N

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