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Fig. 5 | Diabetology & Metabolic Syndrome

Fig. 5

From: Curcumin analog A13 alleviates oxidative stress by activating Nrf2/ARE pathway and ameliorates fibrosis in the myocardium of high-fat-diet and streptozotocin-induced diabetic rats

Fig. 5

Ability of curcumin analog A13 to activate the Nrf2/ARE pathway as detected by Western blot and RT-qPCR. Level of NRF2 in nucleus (a, c) and relative mRNA expresion of Nrf2 (f); Expression of NQO1 and CAT (b, d, e) and relative mRNA expression of Nqo1 and Cat (g, h). All data are presented as mean ± SD. *p < 0.05 versus NC group; #p < 0.05, ##p < 0.01 versus DM group; △p < 0.05, △△p < 0.01 versus DM and CUR groups

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